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Postprandial reduction in blood pressure in the elderly.
N Engl J Med. 1983 Jul 14; 309(2):81-3.NEJM

Abstract

We evaluated the effects of a meal on systolic blood pressure and heart rate in elderly institutionalized subjects (mean age +/- S.E.M., 87 +/- 1) with and without histories of syncope and in young normal subjects. Pulse and blood pressure were measured before the test meal and at intervals for up to 60 minutes afterward. By 35 minutes mean systolic blood pressure had declined a maximum of 25 +/- 5 mm Hg in 10 elderly subjects with syncope and 24 +/- 9 mm Hg in 10 elderly subjects without syncope (P less than 0.03); the level then stabilized without further change until 60 minutes. There were no changes in blood pressure in 11 young subjects or in elderly subjects not given a meal. The postprandial change in systolic pressure was not related to medications or diagnoses. Compensatory cardioacceleration was minimal in the elderly, suggesting impaired baroreflexes. Our observations show that postprandial reductions in blood pressure may predispose the elderly to symptomatic hypotension.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

6855870

Citation

Lipsitz, L A., et al. "Postprandial Reduction in Blood Pressure in the Elderly." The New England Journal of Medicine, vol. 309, no. 2, 1983, pp. 81-3.
Lipsitz LA, Nyquist RP, Wei JY, et al. Postprandial reduction in blood pressure in the elderly. N Engl J Med. 1983;309(2):81-3.
Lipsitz, L. A., Nyquist, R. P., Wei, J. Y., & Rowe, J. W. (1983). Postprandial reduction in blood pressure in the elderly. The New England Journal of Medicine, 309(2), 81-3.
Lipsitz LA, et al. Postprandial Reduction in Blood Pressure in the Elderly. N Engl J Med. 1983 Jul 14;309(2):81-3. PubMed PMID: 6855870.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Postprandial reduction in blood pressure in the elderly. AU - Lipsitz,L A, AU - Nyquist,R P,Jr AU - Wei,J Y, AU - Rowe,J W, PY - 1983/7/14/pubmed PY - 2001/3/28/medline PY - 1983/7/14/entrez SP - 81 EP - 3 JF - The New England journal of medicine JO - N Engl J Med VL - 309 IS - 2 N2 - We evaluated the effects of a meal on systolic blood pressure and heart rate in elderly institutionalized subjects (mean age +/- S.E.M., 87 +/- 1) with and without histories of syncope and in young normal subjects. Pulse and blood pressure were measured before the test meal and at intervals for up to 60 minutes afterward. By 35 minutes mean systolic blood pressure had declined a maximum of 25 +/- 5 mm Hg in 10 elderly subjects with syncope and 24 +/- 9 mm Hg in 10 elderly subjects without syncope (P less than 0.03); the level then stabilized without further change until 60 minutes. There were no changes in blood pressure in 11 young subjects or in elderly subjects not given a meal. The postprandial change in systolic pressure was not related to medications or diagnoses. Compensatory cardioacceleration was minimal in the elderly, suggesting impaired baroreflexes. Our observations show that postprandial reductions in blood pressure may predispose the elderly to symptomatic hypotension. SN - 0028-4793 UR - https://www.unboundmedicine.com/medline/citation/6855870/Postprandial_reduction_in_blood_pressure_in_the_elderly_ L2 - https://www.nejm.org/doi/10.1056/NEJM198307143090205?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -