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Developmental changes in serum ferritin and erythrocyte protoporphyrin in normal (nonanemic) children.
Am J Clin Nutr. 1983 Jul; 38(1):71-6.AJ

Abstract

We studied 4039 children who were 6 months to 12 yr of age to characterize developmental variations of serum ferritin and erythrocyte protoporphyrin. Age-related descriptive statistics were derived. The -2 SD value for serum ferritin was found to increase progressively from 12 to 21 micrograms/1 with increasing age, while the +2 SD value for erythrocyte protoporphyrin was found to decrease progressively from 65 to 42 micrograms/dl whole blood with increasing age. While the mean serum ferritin value was found to continue to rise throughout the first 12 yr of life, erythrocyte protoporphyrin values were highest at 1 to 2 yr of age, then fell to essentially constant levels after 4 to 6 yr of age. These relationships, as well as the linear relationship of increasing hematocrit and serum ferritin with increasing age, suggest that the rise of hematocrit with age, as previously observed, is associated with improving storage and availability of iron for heme synthesis.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

6858956

Citation

Deinard, A S., et al. "Developmental Changes in Serum Ferritin and Erythrocyte Protoporphyrin in Normal (nonanemic) Children." The American Journal of Clinical Nutrition, vol. 38, no. 1, 1983, pp. 71-6.
Deinard AS, Schwartz S, Yip R. Developmental changes in serum ferritin and erythrocyte protoporphyrin in normal (nonanemic) children. Am J Clin Nutr. 1983;38(1):71-6.
Deinard, A. S., Schwartz, S., & Yip, R. (1983). Developmental changes in serum ferritin and erythrocyte protoporphyrin in normal (nonanemic) children. The American Journal of Clinical Nutrition, 38(1), 71-6.
Deinard AS, Schwartz S, Yip R. Developmental Changes in Serum Ferritin and Erythrocyte Protoporphyrin in Normal (nonanemic) Children. Am J Clin Nutr. 1983;38(1):71-6. PubMed PMID: 6858956.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Developmental changes in serum ferritin and erythrocyte protoporphyrin in normal (nonanemic) children. AU - Deinard,A S, AU - Schwartz,S, AU - Yip,R, PY - 1983/7/1/pubmed PY - 1983/7/1/medline PY - 1983/7/1/entrez SP - 71 EP - 6 JF - The American journal of clinical nutrition JO - Am J Clin Nutr VL - 38 IS - 1 N2 - We studied 4039 children who were 6 months to 12 yr of age to characterize developmental variations of serum ferritin and erythrocyte protoporphyrin. Age-related descriptive statistics were derived. The -2 SD value for serum ferritin was found to increase progressively from 12 to 21 micrograms/1 with increasing age, while the +2 SD value for erythrocyte protoporphyrin was found to decrease progressively from 65 to 42 micrograms/dl whole blood with increasing age. While the mean serum ferritin value was found to continue to rise throughout the first 12 yr of life, erythrocyte protoporphyrin values were highest at 1 to 2 yr of age, then fell to essentially constant levels after 4 to 6 yr of age. These relationships, as well as the linear relationship of increasing hematocrit and serum ferritin with increasing age, suggest that the rise of hematocrit with age, as previously observed, is associated with improving storage and availability of iron for heme synthesis. SN - 0002-9165 UR - https://www.unboundmedicine.com/medline/citation/6858956/Developmental_changes_in_serum_ferritin_and_erythrocyte_protoporphyrin_in_normal__nonanemic__children_ L2 - https://academic.oup.com/ajcn/article-lookup/doi/10.1093/ajcn/38.1.71 DB - PRIME DP - Unbound Medicine ER -