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[Cholelithiasis--cholecystectomy and colonic cancer].
Zentralbl Chir. 1983; 108(8):449-56.ZC

Abstract

(1) In 24,089 autopsy records from 1956 to 1979 we found in 16,653 corpses without gallstones 495 = 2.97%, and in 7,436 corpses with gallstones 266 = 3.57% colorectal cancers.--(2) In 503 corpses with previous cholecystectomy performed more than one year before death we found 17 = 3.38% colorectal cancers.--(3) There is no higher incidence of colorectal cancer after cholecystectomy.--(4) In the corpses with gallstones, cholecystectomy or cirrhosis of the gallbladder there were significantly more cancers in the right hemicolon than in corpses without gallstones.--(5) A synetiology by genetic, epidemiologic or (and) metabolic factors may be possible.--(6) A Co-influence of primary bile acids on the genesis of colorectal cancer is discussed.--(7) In patients over 50 years with gallstones it is mandatory for the surgeon to exclude a co-existing colorectal cancer before performing cholecystectomy.

Authors

Schmauss AK
No affiliation info available
Ehrhardt U
No affiliation info available

MeSH

AdolescentAdultAge FactorsAgedBile Acids and SaltsCholecystectomyCholelithiasisColonic NeoplasmsDietary FatsFemaleGallbladder DiseasesHumansMaleMiddle Aged

Pub Type(s)

English Abstract
Journal Article

Language

ger

PubMed ID

6868864

Citation

Schmauss, A K., and U Ehrhardt. "[Cholelithiasis--cholecystectomy and Colonic Cancer]." Zentralblatt Fur Chirurgie, vol. 108, no. 8, 1983, pp. 449-56.
Schmauss AK, Ehrhardt U. [Cholelithiasis--cholecystectomy and colonic cancer]. Zentralbl Chir. 1983;108(8):449-56.
Schmauss, A. K., & Ehrhardt, U. (1983). [Cholelithiasis--cholecystectomy and colonic cancer]. Zentralblatt Fur Chirurgie, 108(8), 449-56.
Schmauss AK, Ehrhardt U. [Cholelithiasis--cholecystectomy and Colonic Cancer]. Zentralbl Chir. 1983;108(8):449-56. PubMed PMID: 6868864.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Cholelithiasis--cholecystectomy and colonic cancer]. AU - Schmauss,A K, AU - Ehrhardt,U, PY - 1983/1/1/pubmed PY - 1983/1/1/medline PY - 1983/1/1/entrez SP - 449 EP - 56 JF - Zentralblatt fur Chirurgie JO - Zentralbl Chir VL - 108 IS - 8 N2 - (1) In 24,089 autopsy records from 1956 to 1979 we found in 16,653 corpses without gallstones 495 = 2.97%, and in 7,436 corpses with gallstones 266 = 3.57% colorectal cancers.--(2) In 503 corpses with previous cholecystectomy performed more than one year before death we found 17 = 3.38% colorectal cancers.--(3) There is no higher incidence of colorectal cancer after cholecystectomy.--(4) In the corpses with gallstones, cholecystectomy or cirrhosis of the gallbladder there were significantly more cancers in the right hemicolon than in corpses without gallstones.--(5) A synetiology by genetic, epidemiologic or (and) metabolic factors may be possible.--(6) A Co-influence of primary bile acids on the genesis of colorectal cancer is discussed.--(7) In patients over 50 years with gallstones it is mandatory for the surgeon to exclude a co-existing colorectal cancer before performing cholecystectomy. SN - 0044-409X UR - https://www.unboundmedicine.com/medline/citation/6868864/[Cholelithiasis__cholecystectomy_and_colonic_cancer]_ L2 - https://medlineplus.gov/gallstones.html DB - PRIME DP - Unbound Medicine ER -