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[Debatable and unclear questions concerning the morphogenesis of cancer of the large intestine and rectum].
Arkh Patol. 1978; 40(5):76-84.AP

Abstract

The analysis of the pertinent literature shows that there is no reliable evidence on the essential importance of intestinal adenomatous polyps in carcinogenesis. The villous and glandular-villous tumours very often are considered to be highly malignant. However the growth pattern as well as histological, iltrastructural, histochemical, immunological, and other characteristics of villous tumours are close to those of adenocarcinomas. Therefore, villous tumours without invasion can be referred to as either carcinoma in situ of superficial cancer. The combination of experimental investigations and studies on human material indicates that colonic cancer prodeminantly develops de novo, that is, without preceeding morphological changes.

Authors

Pozharisskiĭ KM
No affiliation info available

MeSH

AdenocarcinomaAdenomaCarcinomaCarcinoma in SituCell Transformation, NeoplasticColonic NeoplasmsHumansIntestinal PolypsLymphatic MetastasisNeoplasm MetastasisRectal Neoplasms

Pub Type(s)

English Abstract
Journal Article

Language

rus

PubMed ID

686996

Citation

Pozharisskiĭ, K M.. "[Debatable and Unclear Questions Concerning the Morphogenesis of Cancer of the Large Intestine and Rectum]." Arkhiv Patologii, vol. 40, no. 5, 1978, pp. 76-84.
Pozharisskiĭ KM. [Debatable and unclear questions concerning the morphogenesis of cancer of the large intestine and rectum]. Arkh Patol. 1978;40(5):76-84.
Pozharisskiĭ, K. M. (1978). [Debatable and unclear questions concerning the morphogenesis of cancer of the large intestine and rectum]. Arkhiv Patologii, 40(5), 76-84.
Pozharisskiĭ KM. [Debatable and Unclear Questions Concerning the Morphogenesis of Cancer of the Large Intestine and Rectum]. Arkh Patol. 1978;40(5):76-84. PubMed PMID: 686996.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Debatable and unclear questions concerning the morphogenesis of cancer of the large intestine and rectum]. A1 - Pozharisskiĭ,K M, PY - 1978/1/1/pubmed PY - 1978/1/1/medline PY - 1978/1/1/entrez SP - 76 EP - 84 JF - Arkhiv patologii JO - Arkh Patol VL - 40 IS - 5 N2 - The analysis of the pertinent literature shows that there is no reliable evidence on the essential importance of intestinal adenomatous polyps in carcinogenesis. The villous and glandular-villous tumours very often are considered to be highly malignant. However the growth pattern as well as histological, iltrastructural, histochemical, immunological, and other characteristics of villous tumours are close to those of adenocarcinomas. Therefore, villous tumours without invasion can be referred to as either carcinoma in situ of superficial cancer. The combination of experimental investigations and studies on human material indicates that colonic cancer prodeminantly develops de novo, that is, without preceeding morphological changes. SN - 0004-1955 UR - https://www.unboundmedicine.com/medline/citation/686996/[Debatable_and_unclear_questions_concerning_the_morphogenesis_of_cancer_of_the_large_intestine_and_rectum]_ DB - PRIME DP - Unbound Medicine ER -