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Anti tumour and pharmacological effects of the oil from Semecarpus anacardium Linn. f.
Indian J Physiol Pharmacol. 1983 Apr-Jun; 27(2):83-91.IJ

Abstract

Semecarpus anacardium Linn.f. nuts were extracted by using non-polar and polar organic solvents. Hot methanol extract and a resinous fraction, isolated from it, showed antitumour activity against P388 lymphocytic leukaemia in BDF1 mice as judged by their median survival time. Petroleum ether extract and its chromatographically isolated fraction were obtained. The latter fraction was distilled under reduced pressure to get an orange-coloured oil, (b.p. 200-20 degrees/2-3 mm). Both had antitumour activity. The orange-coloured oil, on further distillation under reduced pressure, yielded Bhilawanol. An acetyl derivative of the oil was also obtained. The latter two also had antitumour activity.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

6885136

Citation

Indap, M A., et al. "Anti Tumour and Pharmacological Effects of the Oil From Semecarpus Anacardium Linn. F." Indian Journal of Physiology and Pharmacology, vol. 27, no. 2, 1983, pp. 83-91.
Indap MA, Ambaye RY, Gokhale SV. Anti tumour and pharmacological effects of the oil from Semecarpus anacardium Linn. f. Indian J Physiol Pharmacol. 1983;27(2):83-91.
Indap, M. A., Ambaye, R. Y., & Gokhale, S. V. (1983). Anti tumour and pharmacological effects of the oil from Semecarpus anacardium Linn. f. Indian Journal of Physiology and Pharmacology, 27(2), 83-91.
Indap MA, Ambaye RY, Gokhale SV. Anti Tumour and Pharmacological Effects of the Oil From Semecarpus Anacardium Linn. F. Indian J Physiol Pharmacol. 1983 Apr-Jun;27(2):83-91. PubMed PMID: 6885136.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Anti tumour and pharmacological effects of the oil from Semecarpus anacardium Linn. f. AU - Indap,M A, AU - Ambaye,R Y, AU - Gokhale,S V, PY - 1983/4/1/pubmed PY - 1983/4/1/medline PY - 1983/4/1/entrez SP - 83 EP - 91 JF - Indian journal of physiology and pharmacology JO - Indian J Physiol Pharmacol VL - 27 IS - 2 N2 - Semecarpus anacardium Linn.f. nuts were extracted by using non-polar and polar organic solvents. Hot methanol extract and a resinous fraction, isolated from it, showed antitumour activity against P388 lymphocytic leukaemia in BDF1 mice as judged by their median survival time. Petroleum ether extract and its chromatographically isolated fraction were obtained. The latter fraction was distilled under reduced pressure to get an orange-coloured oil, (b.p. 200-20 degrees/2-3 mm). Both had antitumour activity. The orange-coloured oil, on further distillation under reduced pressure, yielded Bhilawanol. An acetyl derivative of the oil was also obtained. The latter two also had antitumour activity. SN - 0019-5499 UR - https://www.unboundmedicine.com/medline/citation/6885136/Anti_tumour_and_pharmacological_effects_of_the_oil_from_Semecarpus_anacardium_Linn__f_ DB - PRIME DP - Unbound Medicine ER -