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Adenocarcinoma of Bartholin's gland.
Arch Pathol Lab Med. 1980 Oct; 104(10):523-6.AP

Abstract

Bartholin's gland carcinoma is an uncommon disease representing 0.1% of all female genital malignant neoplasms. Five Bartholin's gland adenocarcinomas were selected by the criteria of Chamlian and Taylor. Three patients died from metastatic disease within four years; two are free of apparent disease 14 months and 13 years, respectively, after initial diagnosis. Poor prognosis was associated with large tumor size, poor histopathologic differentiation, and lymph node involvement. Transmission electron microscopy verified the glandular nature of the poorly differentiated lesions. All five tumors demonstrated junctional complexes, abundant rough endoplasmic reticulum, secretory vacuoles, and glandular formation. Low levels of estrogen receptor and moderate levels of progesterone receptor were present in the one case measured. Endogenous peroxidase, and inducible enzyme in estrogen-sensitive tissues, was observed in two of the five tumors.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

6893395

Citation

Mossler, J A., et al. "Adenocarcinoma of Bartholin's Gland." Archives of Pathology & Laboratory Medicine, vol. 104, no. 10, 1980, pp. 523-6.
Mossler JA, Woodard BH, Addison A, et al. Adenocarcinoma of Bartholin's gland. Arch Pathol Lab Med. 1980;104(10):523-6.
Mossler, J. A., Woodard, B. H., Addison, A., & McCarty, K. S. (1980). Adenocarcinoma of Bartholin's gland. Archives of Pathology & Laboratory Medicine, 104(10), 523-6.
Mossler JA, et al. Adenocarcinoma of Bartholin's Gland. Arch Pathol Lab Med. 1980;104(10):523-6. PubMed PMID: 6893395.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Adenocarcinoma of Bartholin's gland. AU - Mossler,J A, AU - Woodard,B H, AU - Addison,A, AU - McCarty,K S,Jr PY - 1980/10/1/pubmed PY - 2001/3/28/medline PY - 1980/10/1/entrez SP - 523 EP - 6 JF - Archives of pathology & laboratory medicine JO - Arch Pathol Lab Med VL - 104 IS - 10 N2 - Bartholin's gland carcinoma is an uncommon disease representing 0.1% of all female genital malignant neoplasms. Five Bartholin's gland adenocarcinomas were selected by the criteria of Chamlian and Taylor. Three patients died from metastatic disease within four years; two are free of apparent disease 14 months and 13 years, respectively, after initial diagnosis. Poor prognosis was associated with large tumor size, poor histopathologic differentiation, and lymph node involvement. Transmission electron microscopy verified the glandular nature of the poorly differentiated lesions. All five tumors demonstrated junctional complexes, abundant rough endoplasmic reticulum, secretory vacuoles, and glandular formation. Low levels of estrogen receptor and moderate levels of progesterone receptor were present in the one case measured. Endogenous peroxidase, and inducible enzyme in estrogen-sensitive tissues, was observed in two of the five tumors. SN - 0003-9985 UR - https://www.unboundmedicine.com/medline/citation/6893395/Adenocarcinoma_of_Bartholin's_gland_ L2 - https://antibodies.cancer.gov/detail/CPTC-PGR-2 DB - PRIME DP - Unbound Medicine ER -