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Impedance plethysmography: the relationship between venous filling and sensitivity and specificity for proximal vein thrombosis.
Circulation. 1978 Nov; 58(5):898-902.Circ

Abstract

We investigated the hypothesis that the diagnostic accuracy of impedance plethysmography (IPG) for thrombosis of the popliteal or more proximal veins increases with enhanced venous filling. Venous filling was increased by prolonging cuff occlusion and by sequential testing. IPG and vengography were performed on 169 legs with and 317 legs without proximal vein thrombosis. The sensitivity and specificity of IPG rose significantly with increased venous filling. Changes in venous filling were associated with corresponding changes in emptying in normal legs, but not those with proximal vein thrombosis, so that the regression lines relating venous filling and emptying in normal and abnormal legs diverged significantly (P less than 0.001). If the IPG sequence had been terminated after only a single 45 second occlusion time test, sensitivity would have deteriorated by 10% and specificity by 20%. These observations indicate that the accuracy of IPG can be significantly enhanced if optimal venous filling is obtained.

Authors

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Pub Type(s)

Journal Article

Language

eng

PubMed ID

699257

Citation

Hull, R, et al. "Impedance Plethysmography: the Relationship Between Venous Filling and Sensitivity and Specificity for Proximal Vein Thrombosis." Circulation, vol. 58, no. 5, 1978, pp. 898-902.
Hull R, Taylor DW, Hirsh J, et al. Impedance plethysmography: the relationship between venous filling and sensitivity and specificity for proximal vein thrombosis. Circulation. 1978;58(5):898-902.
Hull, R., Taylor, D. W., Hirsh, J., Sackett, D. L., Powers, P., Turpie, A. G., & Walker, I. (1978). Impedance plethysmography: the relationship between venous filling and sensitivity and specificity for proximal vein thrombosis. Circulation, 58(5), 898-902.
Hull R, et al. Impedance Plethysmography: the Relationship Between Venous Filling and Sensitivity and Specificity for Proximal Vein Thrombosis. Circulation. 1978;58(5):898-902. PubMed PMID: 699257.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Impedance plethysmography: the relationship between venous filling and sensitivity and specificity for proximal vein thrombosis. AU - Hull,R, AU - Taylor,D W, AU - Hirsh,J, AU - Sackett,D L, AU - Powers,P, AU - Turpie,A G, AU - Walker,I, PY - 1978/11/1/pubmed PY - 1978/11/1/medline PY - 1978/11/1/entrez SP - 898 EP - 902 JF - Circulation JO - Circulation VL - 58 IS - 5 N2 - We investigated the hypothesis that the diagnostic accuracy of impedance plethysmography (IPG) for thrombosis of the popliteal or more proximal veins increases with enhanced venous filling. Venous filling was increased by prolonging cuff occlusion and by sequential testing. IPG and vengography were performed on 169 legs with and 317 legs without proximal vein thrombosis. The sensitivity and specificity of IPG rose significantly with increased venous filling. Changes in venous filling were associated with corresponding changes in emptying in normal legs, but not those with proximal vein thrombosis, so that the regression lines relating venous filling and emptying in normal and abnormal legs diverged significantly (P less than 0.001). If the IPG sequence had been terminated after only a single 45 second occlusion time test, sensitivity would have deteriorated by 10% and specificity by 20%. These observations indicate that the accuracy of IPG can be significantly enhanced if optimal venous filling is obtained. SN - 0009-7322 UR - https://www.unboundmedicine.com/medline/citation/699257/Impedance_plethysmography:_the_relationship_between_venous_filling_and_sensitivity_and_specificity_for_proximal_vein_thrombosis_ L2 - https://www.ahajournals.org/doi/10.1161/01.cir.58.5.898?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -