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Toxic megacolon.
Surg Annu. 1980; 12:341-50.SA

Abstract

Toxic megacolon is a clinical entity characterized by fever, tachycardia, and other toxic symptoms and having as its distinguishing feature dilation of a part or all of the colon. It is the result of the acute onset or exacerbation of ulcerative colitis or, less often, granulomatous enterocolitis, amebiasis, or pseudomembranous colitis. The primary inflammatory disease must be accurately identified, and malignant tumors, such as adenocarcinoma and lymphoma, capable of producing clinical findings similar to those of toxic megacolon must be excluded. Aggressive supportive therapy is essential, and early operation to remove the colon is usually necessary to avoid death as a result of this dreaded complication.

Authors

Thomford NR
No affiliation info available

MeSH

ColectomyColitis, UlcerativeCrohn DiseaseEnterocolitis, PseudomembranousHumansIleostomyMegacolon, ToxicRectum

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

6996173

Citation

Thomford, N R.. "Toxic Megacolon." Surgery Annual, vol. 12, 1980, pp. 341-50.
Thomford NR. Toxic megacolon. Surg Annu. 1980;12:341-50.
Thomford, N. R. (1980). Toxic megacolon. Surgery Annual, 12, 341-50.
Thomford NR. Toxic Megacolon. Surg Annu. 1980;12:341-50. PubMed PMID: 6996173.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Toxic megacolon. A1 - Thomford,N R, PY - 1980/1/1/pubmed PY - 1980/1/1/medline PY - 1980/1/1/entrez SP - 341 EP - 50 JF - Surgery annual JO - Surg Annu VL - 12 N2 - Toxic megacolon is a clinical entity characterized by fever, tachycardia, and other toxic symptoms and having as its distinguishing feature dilation of a part or all of the colon. It is the result of the acute onset or exacerbation of ulcerative colitis or, less often, granulomatous enterocolitis, amebiasis, or pseudomembranous colitis. The primary inflammatory disease must be accurately identified, and malignant tumors, such as adenocarcinoma and lymphoma, capable of producing clinical findings similar to those of toxic megacolon must be excluded. Aggressive supportive therapy is essential, and early operation to remove the colon is usually necessary to avoid death as a result of this dreaded complication. SN - 0081-9638 UR - https://www.unboundmedicine.com/medline/citation/6996173/Toxic_megacolon_ L2 - http://www.diseaseinfosearch.org/result/4555 DB - PRIME DP - Unbound Medicine ER -