Tags

Type your tag names separated by a space and hit enter

[Structural changes in Candida lipolytica cells during citric acid biosynthesis].
Mikrobiologiia. 1981 May-Jun; 50(3):508-14.M

Abstract

The techniques of light and electron microscopy were used to study structural changes in Candida lipolytica cells related to limitation of their growth and a nitrogen source in medium with glucose and hexadecane and transition of the culture to the production of citric acids. Changes in the content of protein in the cell and in the activities of enzymes of the citrate and glyoxylate cycles located in mitochondria and peroxysomes of the yeast were investigated at the same time. The results characterizing cytological changes in the cell of C. lipolytica in the conditions of citric acid biosynthesis fit in well with the data on protein content and enzyme activities in the cells obtained by biochemical analysis. The transition of the yeast cells to the overproduction of citric acids has been shown to be related to profound rearrangements of the cell: the inhibition of protein synthesis; changes in the structure of the cytoplasm; the appearance of vacuoles of an irregular shape, often in contact with the mitochondria; changes in the mitochondrial and peroxysomal apparatus; the accumulation of lipids. It has been demonstrated once again that the peroxysomal apparatus of the yeast cell has a relationship with the metabolism of n-alkanes.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

rus

PubMed ID

7024748

Citation

Kozlova, T M., et al. "[Structural Changes in Candida Lipolytica Cells During Citric Acid Biosynthesis]." Mikrobiologiia, vol. 50, no. 3, 1981, pp. 508-14.
Kozlova TM, Medvedeva GA, Glazunova LM, et al. [Structural changes in Candida lipolytica cells during citric acid biosynthesis]. Mikrobiologiia. 1981;50(3):508-14.
Kozlova, T. M., Medvedeva, G. A., Glazunova, L. M., & Finogenova, T. V. (1981). [Structural changes in Candida lipolytica cells during citric acid biosynthesis]. Mikrobiologiia, 50(3), 508-14.
Kozlova TM, et al. [Structural Changes in Candida Lipolytica Cells During Citric Acid Biosynthesis]. Mikrobiologiia. 1981 May-Jun;50(3):508-14. PubMed PMID: 7024748.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Structural changes in Candida lipolytica cells during citric acid biosynthesis]. AU - Kozlova,T M, AU - Medvedeva,G A, AU - Glazunova,L M, AU - Finogenova,T V, PY - 1981/5/1/pubmed PY - 1981/5/1/medline PY - 1981/5/1/entrez SP - 508 EP - 14 JF - Mikrobiologiia JO - Mikrobiologiia VL - 50 IS - 3 N2 - The techniques of light and electron microscopy were used to study structural changes in Candida lipolytica cells related to limitation of their growth and a nitrogen source in medium with glucose and hexadecane and transition of the culture to the production of citric acids. Changes in the content of protein in the cell and in the activities of enzymes of the citrate and glyoxylate cycles located in mitochondria and peroxysomes of the yeast were investigated at the same time. The results characterizing cytological changes in the cell of C. lipolytica in the conditions of citric acid biosynthesis fit in well with the data on protein content and enzyme activities in the cells obtained by biochemical analysis. The transition of the yeast cells to the overproduction of citric acids has been shown to be related to profound rearrangements of the cell: the inhibition of protein synthesis; changes in the structure of the cytoplasm; the appearance of vacuoles of an irregular shape, often in contact with the mitochondria; changes in the mitochondrial and peroxysomal apparatus; the accumulation of lipids. It has been demonstrated once again that the peroxysomal apparatus of the yeast cell has a relationship with the metabolism of n-alkanes. SN - 0026-3656 UR - https://www.unboundmedicine.com/medline/citation/7024748/[Structural_changes_in_Candida_lipolytica_cells_during_citric_acid_biosynthesis]_ DB - PRIME DP - Unbound Medicine ER -