Tags

Type your tag names separated by a space and hit enter

Infection of Syrian hamsters with lymphocytic choriomeningitis virus: comparison of detection methods.
Am J Vet Res. 1982 Aug; 43(8):1500-2.AJ

Abstract

The prevention of hamster-associated outbreaks of lymphocytic choriomeningitis virus infection in human beings requires rapid and reliable testing of large numbers of hamsters for the infection. To select the most effective test, the antibody response of infected hamsters was determined by the indirect fluorescent antibody and complement-fixation techniques. The indirect fluorescent antibody technique required less than 2 hours to complete, was the first to become positive after infection, and remained positive for at least several months. Infection in hamsters was also readily detected by the inoculation of mice with infected hamster tissues; virus could be isolated from several organs as early as postinoculation day (PID) 3, and all organs tested contained high concentrations of virus by PID 5. After PID 40, virus was detectable only in the kidney; this organ remained positive for over 3 months.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

7049024

Citation

Thacker, W L., et al. "Infection of Syrian Hamsters With Lymphocytic Choriomeningitis Virus: Comparison of Detection Methods." American Journal of Veterinary Research, vol. 43, no. 8, 1982, pp. 1500-2.
Thacker WL, Lewis VJ, Shaddock JH, et al. Infection of Syrian hamsters with lymphocytic choriomeningitis virus: comparison of detection methods. Am J Vet Res. 1982;43(8):1500-2.
Thacker, W. L., Lewis, V. J., Shaddock, J. H., & Winkler, W. G. (1982). Infection of Syrian hamsters with lymphocytic choriomeningitis virus: comparison of detection methods. American Journal of Veterinary Research, 43(8), 1500-2.
Thacker WL, et al. Infection of Syrian Hamsters With Lymphocytic Choriomeningitis Virus: Comparison of Detection Methods. Am J Vet Res. 1982;43(8):1500-2. PubMed PMID: 7049024.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Infection of Syrian hamsters with lymphocytic choriomeningitis virus: comparison of detection methods. AU - Thacker,W L, AU - Lewis,V J, AU - Shaddock,J H, AU - Winkler,W G, PY - 1982/8/1/pubmed PY - 1982/8/1/medline PY - 1982/8/1/entrez SP - 1500 EP - 2 JF - American journal of veterinary research JO - Am. J. Vet. Res. VL - 43 IS - 8 N2 - The prevention of hamster-associated outbreaks of lymphocytic choriomeningitis virus infection in human beings requires rapid and reliable testing of large numbers of hamsters for the infection. To select the most effective test, the antibody response of infected hamsters was determined by the indirect fluorescent antibody and complement-fixation techniques. The indirect fluorescent antibody technique required less than 2 hours to complete, was the first to become positive after infection, and remained positive for at least several months. Infection in hamsters was also readily detected by the inoculation of mice with infected hamster tissues; virus could be isolated from several organs as early as postinoculation day (PID) 3, and all organs tested contained high concentrations of virus by PID 5. After PID 40, virus was detectable only in the kidney; this organ remained positive for over 3 months. SN - 0002-9645 UR - https://www.unboundmedicine.com/medline/citation/7049024/Infection_of_Syrian_hamsters_with_lymphocytic_choriomeningitis_virus:_comparison_of_detection_methods_ DB - PRIME DP - Unbound Medicine ER -