[Carbohydrate infusion in internal diseases. A comparative study in metabolically health, liver diseased and diabetic patients. VII. Infusions of a glucose-fructose-xylitol mixture (relationship 1:2:1) over 48 hours].Infusionsther Klin Ernahr. 1982 Jun; 9(3):112-6.IK
3 groups (6 control persons, 6 patients with liver cirrhosis, 6 patients with diabetes mellitus) were infused with 20% (w/v) carbohydrate mixture (glucose/fructose/xylitol, 1:2:1) for 48 hours. The metabolical status was controlled in defined intervals by means of 39 different laboratory parameters. The infusion rate was supposed to be 0.25 g carbohydrates/kg B. W. and hour. There were no significant changes in blood glucose levels in any of the 3 groups. However we could observe a slight but constant increase in lactate and triglyceride concentrations. Free fatty acids and keton bodies were suppressed on a low level. Only the diabetics showed a significant renal carbohydrate loss with up to 15% of the amount administered. No clinically relevant side effects were observed.