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14C-lactose breath tests during pelvic radiotherapy: the effect of the amount of small bowel irradiated.
Radiology 1982; 142(2):507-10R

Abstract

Thirty patients who were undergoing pelvic radiotherapy had 14C-lactose breath tests performed in the first and fifth weeks of treatment. In Group I (21 patients), a significant portion of the small intestine was irradiated, and in Group II (9 patients), only a small portion of the small intestine was irradiated. In Group I, the average reductions in the excretion of ingested 14C between the first- and fifth-week tests were 41.5% at 1/2 hour postingestion (p less than 0.05), and 21.8% at 1 hour postingestion (p less than 0.05). In Group II, the percentage reductions were 11.8% and 3.7% at 1/2 and 1 hour, respectively (p greater than 0.05). The data suggest that lactose malabsorption is a factor in the etiology of the nausea, vomiting, and diarrhea experienced by patients who are undergoing pelvic radiotherapy, and that the amount of bowel included in the treatment volume significantly influences the degree of malabsorption.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

7054844

Citation

Weiss, R G., and J A. Stryker. "14C-lactose Breath Tests During Pelvic Radiotherapy: the Effect of the Amount of Small Bowel Irradiated." Radiology, vol. 142, no. 2, 1982, pp. 507-10.
Weiss RG, Stryker JA. 14C-lactose breath tests during pelvic radiotherapy: the effect of the amount of small bowel irradiated. Radiology. 1982;142(2):507-10.
Weiss, R. G., & Stryker, J. A. (1982). 14C-lactose breath tests during pelvic radiotherapy: the effect of the amount of small bowel irradiated. Radiology, 142(2), pp. 507-10.
Weiss RG, Stryker JA. 14C-lactose Breath Tests During Pelvic Radiotherapy: the Effect of the Amount of Small Bowel Irradiated. Radiology. 1982;142(2):507-10. PubMed PMID: 7054844.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - 14C-lactose breath tests during pelvic radiotherapy: the effect of the amount of small bowel irradiated. AU - Weiss,R G, AU - Stryker,J A, PY - 1982/2/1/pubmed PY - 1982/2/1/medline PY - 1982/2/1/entrez SP - 507 EP - 10 JF - Radiology JO - Radiology VL - 142 IS - 2 N2 - Thirty patients who were undergoing pelvic radiotherapy had 14C-lactose breath tests performed in the first and fifth weeks of treatment. In Group I (21 patients), a significant portion of the small intestine was irradiated, and in Group II (9 patients), only a small portion of the small intestine was irradiated. In Group I, the average reductions in the excretion of ingested 14C between the first- and fifth-week tests were 41.5% at 1/2 hour postingestion (p less than 0.05), and 21.8% at 1 hour postingestion (p less than 0.05). In Group II, the percentage reductions were 11.8% and 3.7% at 1/2 and 1 hour, respectively (p greater than 0.05). The data suggest that lactose malabsorption is a factor in the etiology of the nausea, vomiting, and diarrhea experienced by patients who are undergoing pelvic radiotherapy, and that the amount of bowel included in the treatment volume significantly influences the degree of malabsorption. SN - 0033-8419 UR - https://www.unboundmedicine.com/medline/citation/7054844/14C_lactose_breath_tests_during_pelvic_radiotherapy:_the_effect_of_the_amount_of_small_bowel_irradiated_ L2 - http://pubs.rsna.org/doi/10.1148/radiology.142.2.7054844?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -