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HLA-A, B, C and HLA-DR antigens in extrinsic allergic alveolitis (budgerigar fancier's lung disease).
Clin Allergy. 1982 Jan; 12(1):47-53.CA

Abstract

Twenty-three patients with extrinsic allergic alveolitis due to an allergy to inhaled budgerigar serum protein (budgerigar fancier's lung disease) were typed for HLA-A, B, C and HLA-DR antigens. Antigen frequencies were compared with those found in 154 healthy control subjects. No statistically significant variation in the frequency of any HLA antigen was detected. Exclusion of two patients who had concurrent coeliac disease, and subdivision of the population into those with acute and chronic disease, failed to reveal any significant association with an HLA specificity. A non-significant increase in B8-DR3 amongst the patients with acute disease was noted. Possible reasons for the apparent HLA associations previously reported by others for extrinsic allergic alveolitis are discussed.

Authors

Muers MF
No affiliation info available
Faux JA
No affiliation info available
Ting A
No affiliation info available
Morris PJ
No affiliation info available

MeSH

Acute DiseaseAgedAlveolitis, Extrinsic AllergicAnimalsBird Fancier's LungCeliac DiseaseChronic DiseaseGene FrequencyGenetic LinkageHLA AntigensHumansParakeetsPulmonary FibrosisRadiography

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

7067067

Citation

Muers, M F., et al. "HLA-A, B, C and HLA-DR Antigens in Extrinsic Allergic Alveolitis (budgerigar Fancier's Lung Disease)." Clinical Allergy, vol. 12, no. 1, 1982, pp. 47-53.
Muers MF, Faux JA, Ting A, et al. HLA-A, B, C and HLA-DR antigens in extrinsic allergic alveolitis (budgerigar fancier's lung disease). Clin Allergy. 1982;12(1):47-53.
Muers, M. F., Faux, J. A., Ting, A., & Morris, P. J. (1982). HLA-A, B, C and HLA-DR antigens in extrinsic allergic alveolitis (budgerigar fancier's lung disease). Clinical Allergy, 12(1), 47-53.
Muers MF, et al. HLA-A, B, C and HLA-DR Antigens in Extrinsic Allergic Alveolitis (budgerigar Fancier's Lung Disease). Clin Allergy. 1982;12(1):47-53. PubMed PMID: 7067067.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - HLA-A, B, C and HLA-DR antigens in extrinsic allergic alveolitis (budgerigar fancier's lung disease). AU - Muers,M F, AU - Faux,J A, AU - Ting,A, AU - Morris,P J, PY - 1982/1/1/pubmed PY - 1982/1/1/medline PY - 1982/1/1/entrez SP - 47 EP - 53 JF - Clinical allergy JO - Clin Allergy VL - 12 IS - 1 N2 - Twenty-three patients with extrinsic allergic alveolitis due to an allergy to inhaled budgerigar serum protein (budgerigar fancier's lung disease) were typed for HLA-A, B, C and HLA-DR antigens. Antigen frequencies were compared with those found in 154 healthy control subjects. No statistically significant variation in the frequency of any HLA antigen was detected. Exclusion of two patients who had concurrent coeliac disease, and subdivision of the population into those with acute and chronic disease, failed to reveal any significant association with an HLA specificity. A non-significant increase in B8-DR3 amongst the patients with acute disease was noted. Possible reasons for the apparent HLA associations previously reported by others for extrinsic allergic alveolitis are discussed. SN - 0009-9090 UR - https://www.unboundmedicine.com/medline/citation/7067067/HLA_A_B_C_and_HLA_DR_antigens_in_extrinsic_allergic_alveolitis__budgerigar_fancier's_lung_disease__ L2 - http://www.diseaseinfosearch.org/result/347 DB - PRIME DP - Unbound Medicine ER -