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Antibodies to pigeon antigens in pigeon breeders. Detection of antibodies by an enzyme-linked immunosorbent assay.
Eur J Respir Dis. 1982 Mar; 63(2):113-21.EJ

Abstract

Antibodies to whole pigeon serum (PS) and pigeon dropping extract (PDE) were investigated in pigeon breeders and controls by an enzyme-linked immunosorbent assay (ELISA). The optimal antigen concentration was in the range of 3-30 microgram protein/ml for both PS and PDE. PDE antibody titres greater than or equal to 10240 were found in three (75%) of four patients with pigeon breeders' disease (PBD) and in 19 (13.6%) of 140 other pigeon breeders (P = 0.011). PS antibody titres greater than or equal to 10240 occurred in all four (100%) PBD patients and in only seven (5.0%) of 140 other breeders (P = 0.0002). In 85 blood donors antibodies in low titres against PS and PDE occurred in 4.7% and 7.1%, respectively. By immunodiffusion three or more precipitin lines were found more often in PBD patients than in other breeders (P = 0.0006), and the highest ELISA antibody titres occurred in patients with precipitating antibodies. No correlation between P blood group phenotypes or anti-P1 antibodies and respiratory symptoms or antibodies to pigeon antigens could be demonstrated.

Authors

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Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

7067762

Citation

Andersen, P, et al. "Antibodies to Pigeon Antigens in Pigeon Breeders. Detection of Antibodies By an Enzyme-linked Immunosorbent Assay." European Journal of Respiratory Diseases, vol. 63, no. 2, 1982, pp. 113-21.
Andersen P, Christensen KM, Jensen BE, et al. Antibodies to pigeon antigens in pigeon breeders. Detection of antibodies by an enzyme-linked immunosorbent assay. Eur J Respir Dis. 1982;63(2):113-21.
Andersen, P., Christensen, K. M., Jensen, B. E., Axél, K., Laursen, J. C., Geday, H., Lundsgaard, A., & Andersen, H. K. (1982). Antibodies to pigeon antigens in pigeon breeders. Detection of antibodies by an enzyme-linked immunosorbent assay. European Journal of Respiratory Diseases, 63(2), 113-21.
Andersen P, et al. Antibodies to Pigeon Antigens in Pigeon Breeders. Detection of Antibodies By an Enzyme-linked Immunosorbent Assay. Eur J Respir Dis. 1982;63(2):113-21. PubMed PMID: 7067762.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antibodies to pigeon antigens in pigeon breeders. Detection of antibodies by an enzyme-linked immunosorbent assay. AU - Andersen,P, AU - Christensen,K M, AU - Jensen,B E, AU - Axél,K, AU - Laursen,J C, AU - Geday,H, AU - Lundsgaard,A, AU - Andersen,H K, PY - 1982/3/1/pubmed PY - 1982/3/1/medline PY - 1982/3/1/entrez SP - 113 EP - 21 JF - European journal of respiratory diseases JO - Eur J Respir Dis VL - 63 IS - 2 N2 - Antibodies to whole pigeon serum (PS) and pigeon dropping extract (PDE) were investigated in pigeon breeders and controls by an enzyme-linked immunosorbent assay (ELISA). The optimal antigen concentration was in the range of 3-30 microgram protein/ml for both PS and PDE. PDE antibody titres greater than or equal to 10240 were found in three (75%) of four patients with pigeon breeders' disease (PBD) and in 19 (13.6%) of 140 other pigeon breeders (P = 0.011). PS antibody titres greater than or equal to 10240 occurred in all four (100%) PBD patients and in only seven (5.0%) of 140 other breeders (P = 0.0002). In 85 blood donors antibodies in low titres against PS and PDE occurred in 4.7% and 7.1%, respectively. By immunodiffusion three or more precipitin lines were found more often in PBD patients than in other breeders (P = 0.0006), and the highest ELISA antibody titres occurred in patients with precipitating antibodies. No correlation between P blood group phenotypes or anti-P1 antibodies and respiratory symptoms or antibodies to pigeon antigens could be demonstrated. SN - 0106-4339 UR - https://www.unboundmedicine.com/medline/citation/7067762/Antibodies_to_pigeon_antigens_in_pigeon_breeders__Detection_of_antibodies_by_an_enzyme_linked_immunosorbent_assay_ DB - PRIME DP - Unbound Medicine ER -