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[Zollinger-Ellison syndrome--changes in surgical therapy. Analysis of 27 patients].
Chirurg. 1982 Apr; 53(4):263-9.C

Abstract

In 10 out of 27 patients with a Zollinger-Ellison syndrome a gastrin-producing tumor was removed, in 5 localized with phlebography. In the remaining 12 patients the diagnosis of a gastrinoma was based on clinical data only. The 10 patients with surgically proven gastrinoma did not differ in their fasting blood-glucose levels, rise of gastrin serum levels after administration of secretin and calcium, in acid production patterns nor in survival time from those 12 patients in whom no gastric-producing tumor had been found. 5 of the 27 patients died, 4 just after surgery. One patient died from advanced malignant disease. In three of our patients localizing diagnostic procedures and consecutive tumor-removal were feasible with the protection of H2-receptor antagonists. The trend in the treatment of ZES goes away from elective total gastrectomy towards conservative treatment with H2-receptor antagonists in view of the low morbidity and the attempt of curative treatment by tumor-removal.

Authors

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Pub Type(s)

English Abstract
Journal Article

Language

ger

PubMed ID

7083968

Citation

Klempa, I, et al. "[Zollinger-Ellison Syndrome--changes in Surgical Therapy. Analysis of 27 Patients]." Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen, vol. 53, no. 4, 1982, pp. 263-9.
Klempa I, Encke A, Classen M, et al. [Zollinger-Ellison syndrome--changes in surgical therapy. Analysis of 27 patients]. Chirurg. 1982;53(4):263-9.
Klempa, I., Encke, A., Classen, M., & Feurle, G. E. (1982). [Zollinger-Ellison syndrome--changes in surgical therapy. Analysis of 27 patients]. Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen, 53(4), 263-9.
Klempa I, et al. [Zollinger-Ellison Syndrome--changes in Surgical Therapy. Analysis of 27 Patients]. Chirurg. 1982;53(4):263-9. PubMed PMID: 7083968.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Zollinger-Ellison syndrome--changes in surgical therapy. Analysis of 27 patients]. AU - Klempa,I, AU - Encke,A, AU - Classen,M, AU - Feurle,G E, PY - 1982/4/1/pubmed PY - 1982/4/1/medline PY - 1982/4/1/entrez SP - 263 EP - 9 JF - Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen JO - Chirurg VL - 53 IS - 4 N2 - In 10 out of 27 patients with a Zollinger-Ellison syndrome a gastrin-producing tumor was removed, in 5 localized with phlebography. In the remaining 12 patients the diagnosis of a gastrinoma was based on clinical data only. The 10 patients with surgically proven gastrinoma did not differ in their fasting blood-glucose levels, rise of gastrin serum levels after administration of secretin and calcium, in acid production patterns nor in survival time from those 12 patients in whom no gastric-producing tumor had been found. 5 of the 27 patients died, 4 just after surgery. One patient died from advanced malignant disease. In three of our patients localizing diagnostic procedures and consecutive tumor-removal were feasible with the protection of H2-receptor antagonists. The trend in the treatment of ZES goes away from elective total gastrectomy towards conservative treatment with H2-receptor antagonists in view of the low morbidity and the attempt of curative treatment by tumor-removal. SN - 0009-4722 UR - https://www.unboundmedicine.com/medline/citation/7083968/[Zollinger_Ellison_syndrome__changes_in_surgical_therapy__Analysis_of_27_patients]_ L2 - http://www.diseaseinfosearch.org/result/7600 DB - PRIME DP - Unbound Medicine ER -