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Ro(SSA) and La(SSB) antibodies in the clinical spectrum of Sjögren's syndrome.
J Rheumatol. 1982 Mar-Apr; 9(2):239-46.JR

Abstract

Seventy-five patients with the symptomatic sicca complex were evaluated clinically and classified as having Sjögren's syndrome (SS) alone or the sicca complex associated with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), progressive systemic sclerosis (PSS) or another connective tissue disorder. Their status with respect to anti-Ro(SSA)/La(SSB) antibodies was determined independent of clinical evaluation and categorization. Overall, 33 (44%) were found to have antibodies to Ro(SSA); and 12 (16%) had antibodies to La(SSB). Anti-Ro antibodies occurred in 50% of those with SS alone as well as in SS associated with RA (39%), SLE (58%), and PSS (20%). Furthermore, patients with SLE without the sicca complex demonstrated antibodies to Ro(SSA) (24%) and La(SSB) (5%). A striking association of anti-Ro(SSA) antibodies in SS with vasculitis is described.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

7097683

Citation

Alexander, E L., et al. "Ro(SSA) and La(SSB) Antibodies in the Clinical Spectrum of Sjögren's Syndrome." The Journal of Rheumatology, vol. 9, no. 2, 1982, pp. 239-46.
Alexander EL, Hirsch TJ, Arnett FC, et al. Ro(SSA) and La(SSB) antibodies in the clinical spectrum of Sjögren's syndrome. J Rheumatol. 1982;9(2):239-46.
Alexander, E. L., Hirsch, T. J., Arnett, F. C., Provost, T. T., & Stevens, M. B. (1982). Ro(SSA) and La(SSB) antibodies in the clinical spectrum of Sjögren's syndrome. The Journal of Rheumatology, 9(2), 239-46.
Alexander EL, et al. Ro(SSA) and La(SSB) Antibodies in the Clinical Spectrum of Sjögren's Syndrome. J Rheumatol. 1982 Mar-Apr;9(2):239-46. PubMed PMID: 7097683.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ro(SSA) and La(SSB) antibodies in the clinical spectrum of Sjögren's syndrome. AU - Alexander,E L, AU - Hirsch,T J, AU - Arnett,F C, AU - Provost,T T, AU - Stevens,M B, PY - 1982/3/1/pubmed PY - 1982/3/1/medline PY - 1982/3/1/entrez SP - 239 EP - 46 JF - The Journal of rheumatology JO - J. Rheumatol. VL - 9 IS - 2 N2 - Seventy-five patients with the symptomatic sicca complex were evaluated clinically and classified as having Sjögren's syndrome (SS) alone or the sicca complex associated with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), progressive systemic sclerosis (PSS) or another connective tissue disorder. Their status with respect to anti-Ro(SSA)/La(SSB) antibodies was determined independent of clinical evaluation and categorization. Overall, 33 (44%) were found to have antibodies to Ro(SSA); and 12 (16%) had antibodies to La(SSB). Anti-Ro antibodies occurred in 50% of those with SS alone as well as in SS associated with RA (39%), SLE (58%), and PSS (20%). Furthermore, patients with SLE without the sicca complex demonstrated antibodies to Ro(SSA) (24%) and La(SSB) (5%). A striking association of anti-Ro(SSA) antibodies in SS with vasculitis is described. SN - 0315-162X UR - https://www.unboundmedicine.com/medline/citation/7097683/Ro_SSA__and_La_SSB__antibodies_in_the_clinical_spectrum_of_Sjögren's_syndrome_ L2 - https://medlineplus.gov/sjogrenssyndrome.html DB - PRIME DP - Unbound Medicine ER -