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Epidemiology of breast cancer.
Clin Obstet Gynecol. 1982 Jun; 25(2):387-92.CO

Abstract

A number of important factors determine the risk for breast cancer, and the most important of these seem to be related to estrogen and possibly prolactin. Additional research is necessary on the role of endogenous and exogenous estrogens and the effect of diet, drugs, and other factors on the levels of estrogen and prolactin. It is unlikely that with present epidemiologic evidence, breast cancer can be prevented. We cannot alter the age of menarche, and promotion of early pregnancy to protect against breast cancer is not feasible. One risk factor that is alterable is obesity, particularly in the postmenopausal woman. The risk factors associated with exogenous estrogens following the menopause require confirmation by other studies. However, because of the strong association of these drugs with increased risk of endometrial cancer, the physician should be cautious in prescribing them.

Authors

No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

7105514

Citation

Marchant, D J.. "Epidemiology of Breast Cancer." Clinical Obstetrics and Gynecology, vol. 25, no. 2, 1982, pp. 387-92.
Marchant DJ. Epidemiology of breast cancer. Clin Obstet Gynecol. 1982;25(2):387-92.
Marchant, D. J. (1982). Epidemiology of breast cancer. Clinical Obstetrics and Gynecology, 25(2), 387-92.
Marchant DJ. Epidemiology of Breast Cancer. Clin Obstet Gynecol. 1982;25(2):387-92. PubMed PMID: 7105514.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Epidemiology of breast cancer. A1 - Marchant,D J, PY - 1982/6/1/pubmed PY - 1982/6/1/medline PY - 1982/6/1/entrez KW - Age Factors KW - Americas KW - Androgens KW - Biology KW - Breast Cancer KW - Cancer KW - Cultural Background KW - Demographic Factors KW - Developed Countries KW - Diseases KW - Endocrine System KW - Epidemiologic Methods KW - Estriol KW - Estrogens KW - Estrone KW - Ethnic Groups KW - Fertility KW - Fertility Measurements KW - Geographic Factors KW - Hormones KW - Incidence KW - Measurement KW - Menarche KW - Menopause KW - Menstruation KW - Neoplasms KW - North America KW - Northern America KW - Obesity KW - Parity KW - Physiology KW - Population KW - Population Characteristics KW - Population Dynamics KW - Progesterone KW - Prolactin KW - Reproduction KW - Research Methodology KW - United States SP - 387 EP - 92 JF - Clinical obstetrics and gynecology JO - Clin Obstet Gynecol VL - 25 IS - 2 N2 - A number of important factors determine the risk for breast cancer, and the most important of these seem to be related to estrogen and possibly prolactin. Additional research is necessary on the role of endogenous and exogenous estrogens and the effect of diet, drugs, and other factors on the levels of estrogen and prolactin. It is unlikely that with present epidemiologic evidence, breast cancer can be prevented. We cannot alter the age of menarche, and promotion of early pregnancy to protect against breast cancer is not feasible. One risk factor that is alterable is obesity, particularly in the postmenopausal woman. The risk factors associated with exogenous estrogens following the menopause require confirmation by other studies. However, because of the strong association of these drugs with increased risk of endometrial cancer, the physician should be cautious in prescribing them. SN - 0009-9201 UR - https://www.unboundmedicine.com/medline/citation/7105514/Epidemiology_of_breast_cancer_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=7105514.ui DB - PRIME DP - Unbound Medicine ER -