Tags

Type your tag names separated by a space and hit enter

Eosinophilic nonallergic rhinitis in children.
Pediatrics. 1982 Sep; 70(3):437-9.Ped

Abstract

Eosinophilic nonallergic rhinitis is a newly described symptom complex reported to occur in a significant percentage of adult patients who have symptoms of perennial rhinitis. They are characterized by nasal eosinophilia, negative allergy skin tests, and a normal serum immunoglobulin E concentration. Twelve children, aged 6 to 17 years, who represent the syndrome of eosinophilic nonallergic rhinitis, have been identified. All have severe perennial rhinitis and nasal eosinophilia. Physical examination revealed pale, boggy membranes with a clear nasal discharge in ten of 12 patients. All 12 patients had a normal serum IgE concentration. All patients initially received an antihistamine-decongestant preparation with subjective improvement in seven of 12 patients. The remaining five patients were placed on a regimen of either topical or systemic steroids and all five had dramatic responses with marked improvement of symptoms. The negative skin tests and normal serum IgE help distinguish this entity from allergic rhinitis, whereas the positive nasal eosinophilia and response to steroids will differentiate eosinophilic nonallergic rhinitis from vasomotor rhinitis. Eosinophilic nonallergic rhinitis is an important cause of perennial rhinitis in children and better knowledge of this entity should lead to more aggressive and efficacious therapy.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

7110818

Citation

Rupp, G H., and R A. Friedman. "Eosinophilic Nonallergic Rhinitis in Children." Pediatrics, vol. 70, no. 3, 1982, pp. 437-9.
Rupp GH, Friedman RA. Eosinophilic nonallergic rhinitis in children. Pediatrics. 1982;70(3):437-9.
Rupp, G. H., & Friedman, R. A. (1982). Eosinophilic nonallergic rhinitis in children. Pediatrics, 70(3), 437-9.
Rupp GH, Friedman RA. Eosinophilic Nonallergic Rhinitis in Children. Pediatrics. 1982;70(3):437-9. PubMed PMID: 7110818.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Eosinophilic nonallergic rhinitis in children. AU - Rupp,G H, AU - Friedman,R A, PY - 1982/9/1/pubmed PY - 1982/9/1/medline PY - 1982/9/1/entrez SP - 437 EP - 9 JF - Pediatrics JO - Pediatrics VL - 70 IS - 3 N2 - Eosinophilic nonallergic rhinitis is a newly described symptom complex reported to occur in a significant percentage of adult patients who have symptoms of perennial rhinitis. They are characterized by nasal eosinophilia, negative allergy skin tests, and a normal serum immunoglobulin E concentration. Twelve children, aged 6 to 17 years, who represent the syndrome of eosinophilic nonallergic rhinitis, have been identified. All have severe perennial rhinitis and nasal eosinophilia. Physical examination revealed pale, boggy membranes with a clear nasal discharge in ten of 12 patients. All 12 patients had a normal serum IgE concentration. All patients initially received an antihistamine-decongestant preparation with subjective improvement in seven of 12 patients. The remaining five patients were placed on a regimen of either topical or systemic steroids and all five had dramatic responses with marked improvement of symptoms. The negative skin tests and normal serum IgE help distinguish this entity from allergic rhinitis, whereas the positive nasal eosinophilia and response to steroids will differentiate eosinophilic nonallergic rhinitis from vasomotor rhinitis. Eosinophilic nonallergic rhinitis is an important cause of perennial rhinitis in children and better knowledge of this entity should lead to more aggressive and efficacious therapy. SN - 0031-4005 UR - https://www.unboundmedicine.com/medline/citation/7110818/Eosinophilic_nonallergic_rhinitis_in_children_ L2 - http://pediatrics.aappublications.org/cgi/pmidlookup?view=long&pmid=7110818 DB - PRIME DP - Unbound Medicine ER -