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In vivo anti-cancer activity of RC-18: a plant isolate from Rubia cordifolia, Linn. against a spectrum of experimental tumour models.
Chemotherapy. 1982; 28(4):291-3.C

Abstract

Anti-tumour activity of RC-18, a pure isolate from Rubia cordifolia was repeatedly tested in different sets of experiments on a spectrum of experimental murine tumours, viz. P388, L1210, L5178Y, B16 melanoma, Lewis lung carcinoma and sarcoma-180. RC-18 exhibited significant increase in life span of ascites leukaemia P388, L1210, L5178Y and a solid tumour B16 melanoma. However, it failed to show any inhibitory effect on solid tumours, Lewis lung carcinoma and sarcoma 180. Promising results against a spectrum of experimental tumours suggest that RC-18 may lead to the development of a potential anti-cancer agent.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

7116981

Citation

Adwankar, M K., and M P. Chitnis. "In Vivo Anti-cancer Activity of RC-18: a Plant Isolate From Rubia Cordifolia, Linn. Against a Spectrum of Experimental Tumour Models." Chemotherapy, vol. 28, no. 4, 1982, pp. 291-3.
Adwankar MK, Chitnis MP. In vivo anti-cancer activity of RC-18: a plant isolate from Rubia cordifolia, Linn. against a spectrum of experimental tumour models. Chemotherapy. 1982;28(4):291-3.
Adwankar, M. K., & Chitnis, M. P. (1982). In vivo anti-cancer activity of RC-18: a plant isolate from Rubia cordifolia, Linn. against a spectrum of experimental tumour models. Chemotherapy, 28(4), 291-3.
Adwankar MK, Chitnis MP. In Vivo Anti-cancer Activity of RC-18: a Plant Isolate From Rubia Cordifolia, Linn. Against a Spectrum of Experimental Tumour Models. Chemotherapy. 1982;28(4):291-3. PubMed PMID: 7116981.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - In vivo anti-cancer activity of RC-18: a plant isolate from Rubia cordifolia, Linn. against a spectrum of experimental tumour models. AU - Adwankar,M K, AU - Chitnis,M P, PY - 1982/1/1/pubmed PY - 1982/1/1/medline PY - 1982/1/1/entrez SP - 291 EP - 3 JF - Chemotherapy JO - Chemotherapy VL - 28 IS - 4 N2 - Anti-tumour activity of RC-18, a pure isolate from Rubia cordifolia was repeatedly tested in different sets of experiments on a spectrum of experimental murine tumours, viz. P388, L1210, L5178Y, B16 melanoma, Lewis lung carcinoma and sarcoma-180. RC-18 exhibited significant increase in life span of ascites leukaemia P388, L1210, L5178Y and a solid tumour B16 melanoma. However, it failed to show any inhibitory effect on solid tumours, Lewis lung carcinoma and sarcoma 180. Promising results against a spectrum of experimental tumours suggest that RC-18 may lead to the development of a potential anti-cancer agent. SN - 0009-3157 UR - https://www.unboundmedicine.com/medline/citation/7116981/In_vivo_anti_cancer_activity_of_RC_18:_a_plant_isolate_from_Rubia_cordifolia_Linn__against_a_spectrum_of_experimental_tumour_models_ L2 - https://www.karger.com?DOI=10.1159/000238092 DB - PRIME DP - Unbound Medicine ER -