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Carboxyhaemoglobin and plasma thiocyanate: complementary indicators of smoking behaviour?
Thorax. 1982 Jul; 37(7):521-5.T

Abstract

Carboxyhaemoglobin and plasma thiocyanate concentrations were measured in 79 non-smokers and 360 cigarette smokers. The mean levels were 0.73% and 7.09% carboxyhaemoglobin and 40 . 2 and 133 . 8 mumol thiocyanate/1 plasma respectively. With 1 . 6% carboxyhaemoglobin and 73 . 0 mumol thiocyanate/1 plasma as critical values the concentrations of carboxyhaemoglobin in 96.6% of subjects and of thiocyanate in 93.4% were compatible with reported smoking status. This difference between the two tests is significant (p less than 0 . 005). Statistical combination of the carboxyhaemoglobin and thiocyanate results, with the use of linear discrimination analysis, only marginally improved their diagnostic efficiency (96.8% of subjects were grouped correctly). This analysis did, however, successfully regroup 21 of 26 individuals with contradictory carboxyhaemoglobin and thiocyanate classifications. It is concluded that in this study determination of thiocyanate added little to the information obtained from carboxyhaemoglobin measurements alone.

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Authors

Saloojee Y
No affiliation info available
Vesey CJ
No affiliation info available
Cole PV
No affiliation info available
Russell MA
No affiliation info available

MeSH

AdultCarboxyhemoglobinFemaleHemoglobinsHumansMaleSmokingStatistics as TopicThiocyanates

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

7135293

Citation

Saloojee, Y, et al. "Carboxyhaemoglobin and Plasma Thiocyanate: Complementary Indicators of Smoking Behaviour?" Thorax, vol. 37, no. 7, 1982, pp. 521-5.
Saloojee Y, Vesey CJ, Cole PV, et al. Carboxyhaemoglobin and plasma thiocyanate: complementary indicators of smoking behaviour? Thorax. 1982;37(7):521-5.
Saloojee, Y., Vesey, C. J., Cole, P. V., & Russell, M. A. (1982). Carboxyhaemoglobin and plasma thiocyanate: complementary indicators of smoking behaviour? Thorax, 37(7), 521-5.
Saloojee Y, et al. Carboxyhaemoglobin and Plasma Thiocyanate: Complementary Indicators of Smoking Behaviour. Thorax. 1982;37(7):521-5. PubMed PMID: 7135293.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Carboxyhaemoglobin and plasma thiocyanate: complementary indicators of smoking behaviour? AU - Saloojee,Y, AU - Vesey,C J, AU - Cole,P V, AU - Russell,M A, PY - 1982/7/1/pubmed PY - 1982/7/1/medline PY - 1982/7/1/entrez SP - 521 EP - 5 JF - Thorax JO - Thorax VL - 37 IS - 7 N2 - Carboxyhaemoglobin and plasma thiocyanate concentrations were measured in 79 non-smokers and 360 cigarette smokers. The mean levels were 0.73% and 7.09% carboxyhaemoglobin and 40 . 2 and 133 . 8 mumol thiocyanate/1 plasma respectively. With 1 . 6% carboxyhaemoglobin and 73 . 0 mumol thiocyanate/1 plasma as critical values the concentrations of carboxyhaemoglobin in 96.6% of subjects and of thiocyanate in 93.4% were compatible with reported smoking status. This difference between the two tests is significant (p less than 0 . 005). Statistical combination of the carboxyhaemoglobin and thiocyanate results, with the use of linear discrimination analysis, only marginally improved their diagnostic efficiency (96.8% of subjects were grouped correctly). This analysis did, however, successfully regroup 21 of 26 individuals with contradictory carboxyhaemoglobin and thiocyanate classifications. It is concluded that in this study determination of thiocyanate added little to the information obtained from carboxyhaemoglobin measurements alone. SN - 0040-6376 UR - https://www.unboundmedicine.com/medline/citation/7135293/Carboxyhaemoglobin_and_plasma_thiocyanate:_complementary_indicators_of_smoking_behaviour L2 - https://thorax.bmj.com/lookup/pmidlookup?view=long&pmid=7135293 DB - PRIME DP - Unbound Medicine ER -