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Distribution of renal cortical and Medullary tissue oxygenation in hemorrhagic shock.
Acta Chir Scand. 1982; 148(3):213-9.AC

Abstract

Renal cortical and medullary tissue oxygen tension, systemic oxygen supply as well as central and renal hemodynamics were investigated in dogs during graded hemorrhage and subsequent reinfusion of shed blood. The measurements of tissue gas tension were carried out by means of implanted Silastic tubes. The baseline renal cortical PO2 was 35 mmHg and the corresponding medullary PO2 25 mmHg. The lowest mean cortical and medullary oxygen tensions--8 and 12 mmHg, respectively--were recorded during the severest hypotension at 40% blood loss. After reinfusions of shed blood the cortical PO2 underwent a transient increase to the original preshock level decreasing slowly thereafter. Concomitantly, the medullary PO2 reached the prehemorrhage value remaining then stationary until the end of the experiment. Arterial blood PO2 was normal throughout the study. Renal venous PO2 fell during the deepest shock but consistently exceeded the corresponding tissue PO2 levels. It is concluded that hemorrhagic hypotension impaired tissue oxygenation of both cortex and medulla, the effect being greatest in the cortex.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

7136420

Citation

Nelimarkka, O, et al. "Distribution of Renal Cortical and Medullary Tissue Oxygenation in Hemorrhagic Shock." Acta Chirurgica Scandinavica, vol. 148, no. 3, 1982, pp. 213-9.
Nelimarkka O, Halkola L, Niinikoski J. Distribution of renal cortical and Medullary tissue oxygenation in hemorrhagic shock. Acta Chir Scand. 1982;148(3):213-9.
Nelimarkka, O., Halkola, L., & Niinikoski, J. (1982). Distribution of renal cortical and Medullary tissue oxygenation in hemorrhagic shock. Acta Chirurgica Scandinavica, 148(3), 213-9.
Nelimarkka O, Halkola L, Niinikoski J. Distribution of Renal Cortical and Medullary Tissue Oxygenation in Hemorrhagic Shock. Acta Chir Scand. 1982;148(3):213-9. PubMed PMID: 7136420.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Distribution of renal cortical and Medullary tissue oxygenation in hemorrhagic shock. AU - Nelimarkka,O, AU - Halkola,L, AU - Niinikoski,J, PY - 1982/1/1/pubmed PY - 1982/1/1/medline PY - 1982/1/1/entrez SP - 213 EP - 9 JF - Acta chirurgica Scandinavica JO - Acta Chir Scand VL - 148 IS - 3 N2 - Renal cortical and medullary tissue oxygen tension, systemic oxygen supply as well as central and renal hemodynamics were investigated in dogs during graded hemorrhage and subsequent reinfusion of shed blood. The measurements of tissue gas tension were carried out by means of implanted Silastic tubes. The baseline renal cortical PO2 was 35 mmHg and the corresponding medullary PO2 25 mmHg. The lowest mean cortical and medullary oxygen tensions--8 and 12 mmHg, respectively--were recorded during the severest hypotension at 40% blood loss. After reinfusions of shed blood the cortical PO2 underwent a transient increase to the original preshock level decreasing slowly thereafter. Concomitantly, the medullary PO2 reached the prehemorrhage value remaining then stationary until the end of the experiment. Arterial blood PO2 was normal throughout the study. Renal venous PO2 fell during the deepest shock but consistently exceeded the corresponding tissue PO2 levels. It is concluded that hemorrhagic hypotension impaired tissue oxygenation of both cortex and medulla, the effect being greatest in the cortex. SN - 0001-5482 UR - https://www.unboundmedicine.com/medline/citation/7136420/Distribution_of_renal_cortical_and_Medullary_tissue_oxygenation_in_hemorrhagic_shock_ DB - PRIME DP - Unbound Medicine ER -