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Estrogen excretion patterns and plasma levels in vegetarian and omnivorous women.
N Engl J Med. 1982 Dec 16; 307(25):1542-7.NEJM

Abstract

We studied 10 vegetarian and 10 nonvegetarian premenopausal women on four occasions approximately four months apart. During each study period, the participants kept three-day dietary records, and estrogens were measured in plasma, urinary, and fecal samples. Vegetarians consumed less total fat than omnivores did (30 per cent of total calories, as compared with 40 per cent) and more dietary fiber (28 g per day, as compared with 12 g). There was a positive correlation between fecal weight and fecal excretion of estrogens in both groups (P less than 0.001), with vegetarians having higher fecal weight and increased fecal excretion of estrogens. Urinary excretion of estriol was lower in vegetarians (P less than 0.05), and their plasma levels of estrone and estradiol were negatively correlated with fecal excretion of estrogen (P = 0.005). Among the vegetarians the beta-glucuronidase activity of fecal bacteria was significantly reduced (P = 0.05). We conclude that vegetarian women have an increased fecal output, which leads to increased fecal excretion of estrogen and a decreased plasma concentration of estrogen.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

7144835

Citation

Goldin, B R., et al. "Estrogen Excretion Patterns and Plasma Levels in Vegetarian and Omnivorous Women." The New England Journal of Medicine, vol. 307, no. 25, 1982, pp. 1542-7.
Goldin BR, Adlercreutz H, Gorbach SL, et al. Estrogen excretion patterns and plasma levels in vegetarian and omnivorous women. N Engl J Med. 1982;307(25):1542-7.
Goldin, B. R., Adlercreutz, H., Gorbach, S. L., Warram, J. H., Dwyer, J. T., Swenson, L., & Woods, M. N. (1982). Estrogen excretion patterns and plasma levels in vegetarian and omnivorous women. The New England Journal of Medicine, 307(25), 1542-7.
Goldin BR, et al. Estrogen Excretion Patterns and Plasma Levels in Vegetarian and Omnivorous Women. N Engl J Med. 1982 Dec 16;307(25):1542-7. PubMed PMID: 7144835.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Estrogen excretion patterns and plasma levels in vegetarian and omnivorous women. AU - Goldin,B R, AU - Adlercreutz,H, AU - Gorbach,S L, AU - Warram,J H, AU - Dwyer,J T, AU - Swenson,L, AU - Woods,M N, PY - 1982/12/16/pubmed PY - 1982/12/16/medline PY - 1982/12/16/entrez SP - 1542 EP - 7 JF - The New England journal of medicine JO - N. Engl. J. Med. VL - 307 IS - 25 N2 - We studied 10 vegetarian and 10 nonvegetarian premenopausal women on four occasions approximately four months apart. During each study period, the participants kept three-day dietary records, and estrogens were measured in plasma, urinary, and fecal samples. Vegetarians consumed less total fat than omnivores did (30 per cent of total calories, as compared with 40 per cent) and more dietary fiber (28 g per day, as compared with 12 g). There was a positive correlation between fecal weight and fecal excretion of estrogens in both groups (P less than 0.001), with vegetarians having higher fecal weight and increased fecal excretion of estrogens. Urinary excretion of estriol was lower in vegetarians (P less than 0.05), and their plasma levels of estrone and estradiol were negatively correlated with fecal excretion of estrogen (P = 0.005). Among the vegetarians the beta-glucuronidase activity of fecal bacteria was significantly reduced (P = 0.05). We conclude that vegetarian women have an increased fecal output, which leads to increased fecal excretion of estrogen and a decreased plasma concentration of estrogen. SN - 0028-4793 UR - https://www.unboundmedicine.com/medline/citation/7144835/Estrogen_excretion_patterns_and_plasma_levels_in_vegetarian_and_omnivorous_women_ L2 - http://www.nejm.org/doi/full/10.1056/NEJM198212163072502?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -