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Mortality among oral-contraceptive users. Royal College of General Practitioners' Oral Contraception Study.
Lancet. 1977 Oct 08; 2(8041):727-31.Lct

Abstract

In a large prospective study carried out in the United Kingdom, the death-rate from diseases of the circulatory system in women who had used oral contraceptives was five times that of controls who had never used them; and the death-rate in those who had taken the pill continuously for 5 years or more was ten times that of the controls. The excess deaths in oral-contraceptive users were due to a wide range of vascular conditions. The total mortality-rate in women who had ever used the pill was increased by 40%, and this was due to an increase in deaths from circulatory diseases of 1 per 5000 ever-users per year. The excess was substantially greater than the death-rate from complications of pregnancy in the controls, and was double the death-rate from accidents. The excess mortality-rate increased with age, cigarette smoking, and duration of oral contraceptive use.

Authors

No affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

71539

Citation

Beral, V. "Mortality Among Oral-contraceptive Users. Royal College of General Practitioners' Oral Contraception Study." Lancet (London, England), vol. 2, no. 8041, 1977, pp. 727-31.
Beral V. Mortality among oral-contraceptive users. Royal College of General Practitioners' Oral Contraception Study. Lancet. 1977;2(8041):727-31.
Beral, V. (1977). Mortality among oral-contraceptive users. Royal College of General Practitioners' Oral Contraception Study. Lancet (London, England), 2(8041), 727-31.
Beral V. Mortality Among Oral-contraceptive Users. Royal College of General Practitioners' Oral Contraception Study. Lancet. 1977 Oct 8;2(8041):727-31. PubMed PMID: 71539.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Mortality among oral-contraceptive users. Royal College of General Practitioners' Oral Contraception Study. A1 - Beral,V, PY - 1977/10/8/pubmed PY - 1977/10/8/medline PY - 1977/10/8/entrez SP - 727 EP - 31 JF - Lancet (London, England) JO - Lancet VL - 2 IS - 8041 N2 - In a large prospective study carried out in the United Kingdom, the death-rate from diseases of the circulatory system in women who had used oral contraceptives was five times that of controls who had never used them; and the death-rate in those who had taken the pill continuously for 5 years or more was ten times that of the controls. The excess deaths in oral-contraceptive users were due to a wide range of vascular conditions. The total mortality-rate in women who had ever used the pill was increased by 40%, and this was due to an increase in deaths from circulatory diseases of 1 per 5000 ever-users per year. The excess was substantially greater than the death-rate from complications of pregnancy in the controls, and was double the death-rate from accidents. The excess mortality-rate increased with age, cigarette smoking, and duration of oral contraceptive use. SN - 0140-6736 UR - https://www.unboundmedicine.com/medline/citation/71539/Mortality_among_oral_contraceptive_users__Royal_College_of_General_Practitioners'_Oral_Contraception_Study_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0140-6736(77)90234-3 DB - PRIME DP - Unbound Medicine ER -