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Blood vitamin status (B1, B2, B6, folic acid and B12) in patients with alcoholic liver disease.
Int J Vitam Nutr Res. 1982; 52(3):266-71.IJ

Abstract

Blood vitamin status (B1, B2, B6, folic acid and B12) was assessed in 41 patients (M = 39; F = 2) with alcoholic liver disease. Biochemical evidence of thiamine deficiency was observed in all groups of patients. Deficiency of riboflavin was detected in patients with histologically normal liver but not in other groups. All the groups were found to be deficient in pyridoxal-5-phosphate--the active form of vitamin B6 (pyridoxine). Serum folate was decreased in all groups except in those with alcoholic hepatitis: red cell folate was, of course within normal limits in all the groups. Vitamin B12 levels were within normal limits in all groups except the cirrhotic one where it was raised. Clinico-biochemical implications of the findings are discussed. Biochemical changes in blood vitamin status may precede clinical manifestations of a disease process and may have prognostic value.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

7174224

Citation

Majumdar, S K., et al. "Blood Vitamin Status (B1, B2, B6, Folic Acid and B12) in Patients With Alcoholic Liver Disease." International Journal for Vitamin and Nutrition Research. Internationale Zeitschrift Fur Vitamin- Und Ernahrungsforschung. Journal International De Vitaminologie Et De Nutrition, vol. 52, no. 3, 1982, pp. 266-71.
Majumdar SK, Shaw GK, O'Gorman P, et al. Blood vitamin status (B1, B2, B6, folic acid and B12) in patients with alcoholic liver disease. Int J Vitam Nutr Res. 1982;52(3):266-71.
Majumdar, S. K., Shaw, G. K., O'Gorman, P., Aps, E. J., Offerman, E. L., & Thomson, A. D. (1982). Blood vitamin status (B1, B2, B6, folic acid and B12) in patients with alcoholic liver disease. International Journal for Vitamin and Nutrition Research. Internationale Zeitschrift Fur Vitamin- Und Ernahrungsforschung. Journal International De Vitaminologie Et De Nutrition, 52(3), 266-71.
Majumdar SK, et al. Blood Vitamin Status (B1, B2, B6, Folic Acid and B12) in Patients With Alcoholic Liver Disease. Int J Vitam Nutr Res. 1982;52(3):266-71. PubMed PMID: 7174224.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Blood vitamin status (B1, B2, B6, folic acid and B12) in patients with alcoholic liver disease. AU - Majumdar,S K, AU - Shaw,G K, AU - O'Gorman,P, AU - Aps,E J, AU - Offerman,E L, AU - Thomson,A D, PY - 1982/1/1/pubmed PY - 1982/1/1/medline PY - 1982/1/1/entrez SP - 266 EP - 71 JF - International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition JO - Int J Vitam Nutr Res VL - 52 IS - 3 N2 - Blood vitamin status (B1, B2, B6, folic acid and B12) was assessed in 41 patients (M = 39; F = 2) with alcoholic liver disease. Biochemical evidence of thiamine deficiency was observed in all groups of patients. Deficiency of riboflavin was detected in patients with histologically normal liver but not in other groups. All the groups were found to be deficient in pyridoxal-5-phosphate--the active form of vitamin B6 (pyridoxine). Serum folate was decreased in all groups except in those with alcoholic hepatitis: red cell folate was, of course within normal limits in all the groups. Vitamin B12 levels were within normal limits in all groups except the cirrhotic one where it was raised. Clinico-biochemical implications of the findings are discussed. Biochemical changes in blood vitamin status may precede clinical manifestations of a disease process and may have prognostic value. SN - 0300-9831 UR - https://www.unboundmedicine.com/medline/citation/7174224/Blood_vitamin_status__B1_B2_B6_folic_acid_and_B12__in_patients_with_alcoholic_liver_disease_ L2 - http://www.diseaseinfosearch.org/result/4280 DB - PRIME DP - Unbound Medicine ER -