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The role of herd immunity in control of measles.
Yale J Biol Med. 1982 May-Aug; 55(3-4):351-60.YJ

Abstract

Measles vaccine cannot give high sero-conversion rates in developing countries. The high birth rates characteristic of these countries lead to infection at a very early age, thus making it difficult to vaccinate before exposure to the disease. Nevertheless, if given early in life, the vaccine can reduce the rate of virus circulation and thus raise the age at which children are infected. Once that is done, higher sero-conversion rates can be obtained by raising the age at vaccination. During the period when vaccine is given at an early age, the titers in responding children will be low, and this will leave children of the next generation with little protection. It is important, therefore, that if vaccine is used early the program be intensively and consistently applied to control virus circulation before the next generation is born.

Authors

No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

7180027

Citation

Black, F L.. "The Role of Herd Immunity in Control of Measles." The Yale Journal of Biology and Medicine, vol. 55, no. 3-4, 1982, pp. 351-60.
Black FL. The role of herd immunity in control of measles. Yale J Biol Med. 1982;55(3-4):351-60.
Black, F. L. (1982). The role of herd immunity in control of measles. The Yale Journal of Biology and Medicine, 55(3-4), 351-60.
Black FL. The Role of Herd Immunity in Control of Measles. Yale J Biol Med. 1982 May-Aug;55(3-4):351-60. PubMed PMID: 7180027.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The role of herd immunity in control of measles. A1 - Black,F L, PY - 1982/5/1/pubmed PY - 1982/5/1/medline PY - 1982/5/1/entrez KW - Age Factors KW - Biology KW - Child Health KW - Communicable Disease Control KW - Delivery Of Health Care KW - Demographic Factors KW - Developing Countries KW - Diseases KW - Health KW - Health Services KW - Immunity KW - Immunization KW - Measles--prevention and control KW - Medicine KW - Physiology KW - Population KW - Population Characteristics KW - Preventive Medicine KW - Primary Health Care KW - Public Health KW - Vaccination KW - Viral Diseases SP - 351 EP - 60 JF - The Yale journal of biology and medicine JO - Yale J Biol Med VL - 55 IS - 3-4 N2 - Measles vaccine cannot give high sero-conversion rates in developing countries. The high birth rates characteristic of these countries lead to infection at a very early age, thus making it difficult to vaccinate before exposure to the disease. Nevertheless, if given early in life, the vaccine can reduce the rate of virus circulation and thus raise the age at which children are infected. Once that is done, higher sero-conversion rates can be obtained by raising the age at vaccination. During the period when vaccine is given at an early age, the titers in responding children will be low, and this will leave children of the next generation with little protection. It is important, therefore, that if vaccine is used early the program be intensively and consistently applied to control virus circulation before the next generation is born. SN - 0044-0086 UR - https://www.unboundmedicine.com/medline/citation/7180027/The_role_of_herd_immunity_in_control_of_measles_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/7180027/ DB - PRIME DP - Unbound Medicine ER -