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Hematoporphyrin derivative in the detection and localization of radiographically occult lung cancer.
Am Rev Respir Dis. 1982 Dec; 126(6):1087-8.AR

Abstract

Hematoporphyrin derivative used in conjunction with the Mayo Clinic bronchofiberscopic fluorescence detection system allows accurate localization of radiographically occult early squamous cell carcinoma. Thirteen tumors were localized in 10 patients with radiographically occult lung cancer. Six were in situ with or without microinvasion and were also bronchoscopically occult. Localization of these 6 tumors was expedited by the use of hematoporphyrin derivative and the bronchoscopic fluorescence detection system. Hematoporphyrin-derivative fluorescence was not specific for carcinoma and was also detected in areas of moderate and marked squamous cellular atypia. Thus, although detection of hematoporphyrin-derivative fluorescence suggests the presence of cancer, proof depends on histologic or cytologic confirmation.

Authors

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Pub Type(s)

Journal Article

Language

eng

PubMed ID

7181227

Citation

Cortese, D A., et al. "Hematoporphyrin Derivative in the Detection and Localization of Radiographically Occult Lung Cancer." The American Review of Respiratory Disease, vol. 126, no. 6, 1982, pp. 1087-8.
Cortese DA, Kinsey JH, Woolner LB, et al. Hematoporphyrin derivative in the detection and localization of radiographically occult lung cancer. Am Rev Respir Dis. 1982;126(6):1087-8.
Cortese, D. A., Kinsey, J. H., Woolner, L. B., Sanderson, D. R., & Fontana, R. S. (1982). Hematoporphyrin derivative in the detection and localization of radiographically occult lung cancer. The American Review of Respiratory Disease, 126(6), 1087-8.
Cortese DA, et al. Hematoporphyrin Derivative in the Detection and Localization of Radiographically Occult Lung Cancer. Am Rev Respir Dis. 1982;126(6):1087-8. PubMed PMID: 7181227.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hematoporphyrin derivative in the detection and localization of radiographically occult lung cancer. AU - Cortese,D A, AU - Kinsey,J H, AU - Woolner,L B, AU - Sanderson,D R, AU - Fontana,R S, PY - 1982/12/1/pubmed PY - 1982/12/1/medline PY - 1982/12/1/entrez SP - 1087 EP - 8 JF - The American review of respiratory disease JO - Am. Rev. Respir. Dis. VL - 126 IS - 6 N2 - Hematoporphyrin derivative used in conjunction with the Mayo Clinic bronchofiberscopic fluorescence detection system allows accurate localization of radiographically occult early squamous cell carcinoma. Thirteen tumors were localized in 10 patients with radiographically occult lung cancer. Six were in situ with or without microinvasion and were also bronchoscopically occult. Localization of these 6 tumors was expedited by the use of hematoporphyrin derivative and the bronchoscopic fluorescence detection system. Hematoporphyrin-derivative fluorescence was not specific for carcinoma and was also detected in areas of moderate and marked squamous cellular atypia. Thus, although detection of hematoporphyrin-derivative fluorescence suggests the presence of cancer, proof depends on histologic or cytologic confirmation. SN - 0003-0805 UR - https://www.unboundmedicine.com/medline/citation/7181227/Hematoporphyrin_derivative_in_the_detection_and_localization_of_radiographically_occult_lung_cancer_ L2 - http://www.atsjournals.org/doi/full/10.1164/arrd.1982.126.6.1087?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -