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[Familial incidence of bird-breeder's lung and HLA (author's transl)].
Med Clin (Barc). 1981 Mar 10; 76(5):221-2.MC

Abstract

The cases of two siblings affected with bird-breeder's lung are reported. The analysis of their HLA group demonstrated that both belonged to the haplotype HLA Bw15. The finding of a familial incidence of this type of alveolitis favors the presence of a genetic susceptibility for the disease. The same HLA group has been found in the rare families heretofore reported with bird-breeder's lung. Given that the pathogenesis of extrinsic allergic alveolitis has recently been linked to cellular immunity (T cells), and that the presence of a common HLA haplotype in patients suffering from bird-breeder's lung is related to the capacity for an immune response in general, and to the cellular immune response in particular, the presence of a genetic susceptibility in this disease appears as very likely, although the influence of other factors can not be ruled out.

Authors

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Pub Type(s)

Case Reports
English Abstract
Journal Article

Language

spa

PubMed ID

7206891

Citation

Morell, F, et al. "[Familial Incidence of Bird-breeder's Lung and HLA (author's Transl)]." Medicina Clinica, vol. 76, no. 5, 1981, pp. 221-2.
Morell F, Morera J, Orriols R, et al. [Familial incidence of bird-breeder's lung and HLA (author's transl)]. Med Clin (Barc). 1981;76(5):221-2.
Morell, F., Morera, J., Orriols, R., Mercader, J., & Aranda, A. (1981). [Familial incidence of bird-breeder's lung and HLA (author's transl)]. Medicina Clinica, 76(5), 221-2.
Morell F, et al. [Familial Incidence of Bird-breeder's Lung and HLA (author's Transl)]. Med Clin (Barc). 1981 Mar 10;76(5):221-2. PubMed PMID: 7206891.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Familial incidence of bird-breeder's lung and HLA (author's transl)]. AU - Morell,F, AU - Morera,J, AU - Orriols,R, AU - Mercader,J, AU - Aranda,A, PY - 1981/3/10/pubmed PY - 1981/3/10/medline PY - 1981/3/10/entrez SP - 221 EP - 2 JF - Medicina clinica JO - Med Clin (Barc) VL - 76 IS - 5 N2 - The cases of two siblings affected with bird-breeder's lung are reported. The analysis of their HLA group demonstrated that both belonged to the haplotype HLA Bw15. The finding of a familial incidence of this type of alveolitis favors the presence of a genetic susceptibility for the disease. The same HLA group has been found in the rare families heretofore reported with bird-breeder's lung. Given that the pathogenesis of extrinsic allergic alveolitis has recently been linked to cellular immunity (T cells), and that the presence of a common HLA haplotype in patients suffering from bird-breeder's lung is related to the capacity for an immune response in general, and to the cellular immune response in particular, the presence of a genetic susceptibility in this disease appears as very likely, although the influence of other factors can not be ruled out. SN - 0025-7753 UR - https://www.unboundmedicine.com/medline/citation/7206891/[Familial_incidence_of_bird_breeder's_lung_and_HLA__author's_transl_]_ L2 - https://antibodies.cancer.gov/detail/CPTC-HLA-DPB1-2 DB - PRIME DP - Unbound Medicine ER -