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Selective IgA deficiency and the HLA-B8 antigen. Report of two cases with familial data.
Arch Intern Med 1981; 141(4):509-10AI

Abstract

Two patients had IgA deficiency, giardiasis, and the HLA-B8 antigen. The family of patient 1 included members with juvenile-onset diabetes mellitus, adrenal insufficiency, pernicious anemia, and hypothyroidism, a combination of unusual diseases that has been reported previously to occur as a syndrome with IgA deficiency and the HLA-B8 antigen. This coincidence makes it likely that these two patients and the one family previously described have a common pathogenic base, the inheritance of an abnormal immune-response gene that is acquired with the HLA-B8 antigen as a result of genetic dysequilibrium.

Authors

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Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

7212894

Citation

Perez-Jimenez, F, et al. "Selective IgA Deficiency and the HLA-B8 Antigen. Report of Two Cases With Familial Data." Archives of Internal Medicine, vol. 141, no. 4, 1981, pp. 509-10.
Perez-Jimenez F, Lopez PB, Tallo EP, et al. Selective IgA deficiency and the HLA-B8 antigen. Report of two cases with familial data. Arch Intern Med. 1981;141(4):509-10.
Perez-Jimenez, F., Lopez, P. B., Tallo, E. P., Guzman, J. R., Molina, J. S., & Pereperez, J. A. (1981). Selective IgA deficiency and the HLA-B8 antigen. Report of two cases with familial data. Archives of Internal Medicine, 141(4), pp. 509-10.
Perez-Jimenez F, et al. Selective IgA Deficiency and the HLA-B8 Antigen. Report of Two Cases With Familial Data. Arch Intern Med. 1981;141(4):509-10. PubMed PMID: 7212894.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Selective IgA deficiency and the HLA-B8 antigen. Report of two cases with familial data. AU - Perez-Jimenez,F, AU - Lopez,P B, AU - Tallo,E P, AU - Guzman,J R, AU - Molina,J S, AU - Pereperez,J A, PY - 1981/3/1/pubmed PY - 1981/3/1/medline PY - 1981/3/1/entrez SP - 509 EP - 10 JF - Archives of internal medicine JO - Arch. Intern. Med. VL - 141 IS - 4 N2 - Two patients had IgA deficiency, giardiasis, and the HLA-B8 antigen. The family of patient 1 included members with juvenile-onset diabetes mellitus, adrenal insufficiency, pernicious anemia, and hypothyroidism, a combination of unusual diseases that has been reported previously to occur as a syndrome with IgA deficiency and the HLA-B8 antigen. This coincidence makes it likely that these two patients and the one family previously described have a common pathogenic base, the inheritance of an abnormal immune-response gene that is acquired with the HLA-B8 antigen as a result of genetic dysequilibrium. SN - 0003-9926 UR - https://www.unboundmedicine.com/medline/citation/7212894/Selective_IgA_deficiency_and_the_HLA_B8_antigen__Report_of_two_cases_with_familial_data_ L2 - https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/vol/141/pg/509 DB - PRIME DP - Unbound Medicine ER -