Tags

Type your tag names separated by a space and hit enter

Comparison of oral glucose tolerance tests and mixed meals in patients with apparent idiopathic postabsorptive hypoglycemia: absence of hypoglycemia after meals.
Diabetes. 1981 Jun; 30(6):465-70.D

Abstract

The relationship between symptoms of idiopathic postabsorptive hypoglycemia and glucose homeostasis was evaluated by giving oral glucose tolerance tests (OGTT) and mixed meals to 18 patients and 16 controls. Chemical hypoglycemia after OGTT occurred as often in patients referred because of possible hypoglycemia symptoms, 18 out of 80 (23%), as in controls, 4 out of 16 (25%). After glucose, patients showed both clinical and chemical hypoglycemia (mean +/- SE plasma glucose, 48 +/- 3 mg/dl), but insulin, glucagon, and growth hormone responses were similar to controls. After mixed meals, no chemical hypoglycemia occurred in patients (mean plasma glucose, 79 +/- 3 mg/dl), yet 14 out of 18 (78%) had symptoms and/or signs consistent with hypoglycemia. No abnormality of glucose homeostasis was observed after meals that could account for symptoms or signs experienced by patients with idiopathic postabsorptive hypoglycemia. Since factors other than hypoglycemia appear to be involved, the disorder should be termed the idiopathic postprandial syndrome to avoid the connotation of chemical hypoglycemia.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

7227659

Citation

Charles, M A., et al. "Comparison of Oral Glucose Tolerance Tests and Mixed Meals in Patients With Apparent Idiopathic Postabsorptive Hypoglycemia: Absence of Hypoglycemia After Meals." Diabetes, vol. 30, no. 6, 1981, pp. 465-70.
Charles MA, Hofeldt F, Shackelford A, et al. Comparison of oral glucose tolerance tests and mixed meals in patients with apparent idiopathic postabsorptive hypoglycemia: absence of hypoglycemia after meals. Diabetes. 1981;30(6):465-70.
Charles, M. A., Hofeldt, F., Shackelford, A., Waldeck, N., Dodson, L. E., Bunker, D., Coggins, J. T., & Eichner, H. (1981). Comparison of oral glucose tolerance tests and mixed meals in patients with apparent idiopathic postabsorptive hypoglycemia: absence of hypoglycemia after meals. Diabetes, 30(6), 465-70.
Charles MA, et al. Comparison of Oral Glucose Tolerance Tests and Mixed Meals in Patients With Apparent Idiopathic Postabsorptive Hypoglycemia: Absence of Hypoglycemia After Meals. Diabetes. 1981;30(6):465-70. PubMed PMID: 7227659.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of oral glucose tolerance tests and mixed meals in patients with apparent idiopathic postabsorptive hypoglycemia: absence of hypoglycemia after meals. AU - Charles,M A, AU - Hofeldt,F, AU - Shackelford,A, AU - Waldeck,N, AU - Dodson,L E,Jr AU - Bunker,D, AU - Coggins,J T, AU - Eichner,H, PY - 1981/6/1/pubmed PY - 2001/3/28/medline PY - 1981/6/1/entrez SP - 465 EP - 70 JF - Diabetes JO - Diabetes VL - 30 IS - 6 N2 - The relationship between symptoms of idiopathic postabsorptive hypoglycemia and glucose homeostasis was evaluated by giving oral glucose tolerance tests (OGTT) and mixed meals to 18 patients and 16 controls. Chemical hypoglycemia after OGTT occurred as often in patients referred because of possible hypoglycemia symptoms, 18 out of 80 (23%), as in controls, 4 out of 16 (25%). After glucose, patients showed both clinical and chemical hypoglycemia (mean +/- SE plasma glucose, 48 +/- 3 mg/dl), but insulin, glucagon, and growth hormone responses were similar to controls. After mixed meals, no chemical hypoglycemia occurred in patients (mean plasma glucose, 79 +/- 3 mg/dl), yet 14 out of 18 (78%) had symptoms and/or signs consistent with hypoglycemia. No abnormality of glucose homeostasis was observed after meals that could account for symptoms or signs experienced by patients with idiopathic postabsorptive hypoglycemia. Since factors other than hypoglycemia appear to be involved, the disorder should be termed the idiopathic postprandial syndrome to avoid the connotation of chemical hypoglycemia. SN - 0012-1797 UR - https://www.unboundmedicine.com/medline/citation/7227659/Comparison_of_oral_glucose_tolerance_tests_and_mixed_meals_in_patients_with_apparent_idiopathic_postabsorptive_hypoglycemia:_absence_of_hypoglycemia_after_meals_ L2 - https://diabetes.diabetesjournals.org/lookup/pmidlookup?view=long&pmid=7227659 DB - PRIME DP - Unbound Medicine ER -