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Generalized acanthosis nigricans.
Dermatologica. 1981; 163(1):19-24.D

Abstract

A patient suffering from an advanced and inoperable gastric carcinoma developed an unusual paraneoplastic syndrome, consisting of intensive pruritus, acanthosis nigricans, sign of Leser-Trélat (seborrhoic keratoses and freckles), warty and papillomatous excrescences, palmoplantar hyperkeratosis and florid papillomatous and granular lesions of the mouth mucosa. The whole skin of the patient was involved. The authors believe this disorder to be generalized acanthosis nigricans. As a cause they suggest the possibility of a growth-stimulating factor, produced by the tumor cells. The relationship of acanthosis nigricans with the sign of Leser-Trélat is discussed.

Authors

Andreev VC
No affiliation info available
Boyanov L
No affiliation info available
Tsankov N
No affiliation info available

MeSH

Acanthosis NigricansGrowth SubstancesHumansMaleMiddle AgedParaneoplastic SyndromesStomach Neoplasms

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

7274513

Citation

Andreev, V C., et al. "Generalized Acanthosis Nigricans." Dermatologica, vol. 163, no. 1, 1981, pp. 19-24.
Andreev VC, Boyanov L, Tsankov N. Generalized acanthosis nigricans. Dermatologica. 1981;163(1):19-24.
Andreev, V. C., Boyanov, L., & Tsankov, N. (1981). Generalized acanthosis nigricans. Dermatologica, 163(1), 19-24.
Andreev VC, Boyanov L, Tsankov N. Generalized Acanthosis Nigricans. Dermatologica. 1981;163(1):19-24. PubMed PMID: 7274513.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Generalized acanthosis nigricans. AU - Andreev,V C, AU - Boyanov,L, AU - Tsankov,N, PY - 1981/1/1/pubmed PY - 1981/1/1/medline PY - 1981/1/1/entrez SP - 19 EP - 24 JF - Dermatologica JO - Dermatologica VL - 163 IS - 1 N2 - A patient suffering from an advanced and inoperable gastric carcinoma developed an unusual paraneoplastic syndrome, consisting of intensive pruritus, acanthosis nigricans, sign of Leser-Trélat (seborrhoic keratoses and freckles), warty and papillomatous excrescences, palmoplantar hyperkeratosis and florid papillomatous and granular lesions of the mouth mucosa. The whole skin of the patient was involved. The authors believe this disorder to be generalized acanthosis nigricans. As a cause they suggest the possibility of a growth-stimulating factor, produced by the tumor cells. The relationship of acanthosis nigricans with the sign of Leser-Trélat is discussed. SN - 0011-9075 UR - https://www.unboundmedicine.com/medline/citation/7274513/Generalized_acanthosis_nigricans_ L2 - http://www.diseaseinfosearch.org/result/90 DB - PRIME DP - Unbound Medicine ER -