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Establishment of normal values in adults for zinc protoporphyrin (ZPP) using hematofluorometer: correlation with normal blood lead values.
Am Ind Hyg Assoc J. 1981 Sep; 42(9):637-42.AI

Abstract

Zinc protoporphyrin (ZPP) values were analyzed with a hematofluorometer on 395 non-occupationally lead exposed subjects. Blood lead (B-Pb) determinations were concurrently carried out with an extraction procedure using flameless atomic absorption method. Applying Hoffman's Statistical Analysis with a logarithmic transformation, a normal range for ZPP (a mean of 23 microgram/dL) was established with 40 microgram ZPP/dL on the upper limit of the 95% probability range. A value of 54 microgram ZPP/dL has been found to be a suitable cutoff value above which one generally finds B-Pb values greater than 40 microgram/dL. For B-Pb values (less than 40 microgram/dL) and ZPP values in our normal range, there was essentially no correlation. However, for elevated values of both, a correlation coefficient of 0.87 was found for log ZZP versus B-Pb. ZPP values for males appeared to increase with increasing age.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

7293926

Citation

Suga, R S., et al. "Establishment of Normal Values in Adults for Zinc Protoporphyrin (ZPP) Using Hematofluorometer: Correlation With Normal Blood Lead Values." American Industrial Hygiene Association Journal, vol. 42, no. 9, 1981, pp. 637-42.
Suga RS, Fischinger AJ, Knoch FW. Establishment of normal values in adults for zinc protoporphyrin (ZPP) using hematofluorometer: correlation with normal blood lead values. Am Ind Hyg Assoc J. 1981;42(9):637-42.
Suga, R. S., Fischinger, A. J., & Knoch, F. W. (1981). Establishment of normal values in adults for zinc protoporphyrin (ZPP) using hematofluorometer: correlation with normal blood lead values. American Industrial Hygiene Association Journal, 42(9), 637-42.
Suga RS, Fischinger AJ, Knoch FW. Establishment of Normal Values in Adults for Zinc Protoporphyrin (ZPP) Using Hematofluorometer: Correlation With Normal Blood Lead Values. Am Ind Hyg Assoc J. 1981;42(9):637-42. PubMed PMID: 7293926.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Establishment of normal values in adults for zinc protoporphyrin (ZPP) using hematofluorometer: correlation with normal blood lead values. AU - Suga,R S, AU - Fischinger,A J, AU - Knoch,F W, PY - 1981/9/1/pubmed PY - 1981/9/1/medline PY - 1981/9/1/entrez SP - 637 EP - 42 JF - American Industrial Hygiene Association journal JO - Am Ind Hyg Assoc J VL - 42 IS - 9 N2 - Zinc protoporphyrin (ZPP) values were analyzed with a hematofluorometer on 395 non-occupationally lead exposed subjects. Blood lead (B-Pb) determinations were concurrently carried out with an extraction procedure using flameless atomic absorption method. Applying Hoffman's Statistical Analysis with a logarithmic transformation, a normal range for ZPP (a mean of 23 microgram/dL) was established with 40 microgram ZPP/dL on the upper limit of the 95% probability range. A value of 54 microgram ZPP/dL has been found to be a suitable cutoff value above which one generally finds B-Pb values greater than 40 microgram/dL. For B-Pb values (less than 40 microgram/dL) and ZPP values in our normal range, there was essentially no correlation. However, for elevated values of both, a correlation coefficient of 0.87 was found for log ZZP versus B-Pb. ZPP values for males appeared to increase with increasing age. SN - 0002-8894 UR - https://www.unboundmedicine.com/medline/citation/7293926/Establishment_of_normal_values_in_adults_for_zinc_protoporphyrin__ZPP__using_hematofluorometer:_correlation_with_normal_blood_lead_values_ DB - PRIME DP - Unbound Medicine ER -