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Iron absorption in relation to iron status. Model proposed to express results to food iron absorption measurements.
Scand J Haematol. 1981 Sep; 27(3):201-8.SJ

Abstract

The absorption from a 3 mg dose of ferrous iron was measured in 250 male subjects. The absorption was related to the log concentration of serum ferritin in 186 subjects of whom 99 were regular blood donors (r = -0.76), and to bone marrow haemosiderin grading in 52 subjects with varying iron status. The purpose was to try and establish a percentage absorption from such a dose that is representative of subjects who are borderline iron deficient. This information is necessary for food iron absorption studies in order (1) to calculate the absorption of iron from the diet at a given iron status and (2) compare the absorption of iron from different meals studied in different groups of subjects by different investigators. The results suggest that an absorption of about 40% of a 3 mg reference dose of ferrous iron is given in a fasting state, roughly corresponds to the absorption in borderline-iron-deficient subjects. The results indicate that this 40% absorption value corresponds to a serum ferritin level of 30 microgram/l and that food iron absorption in a group of subjects should be expressed preferably as the absorption corresponding to a reference-dose absorption of 40%, or possibly a serum ferritin level of 30 microgram/l.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

7313546

Citation

Magnusson, B, et al. "Iron Absorption in Relation to Iron Status. Model Proposed to Express Results to Food Iron Absorption Measurements." Scandinavian Journal of Haematology, vol. 27, no. 3, 1981, pp. 201-8.
Magnusson B, Björn-Rassmussen E, Hallberg L, et al. Iron absorption in relation to iron status. Model proposed to express results to food iron absorption measurements. Scand J Haematol. 1981;27(3):201-8.
Magnusson, B., Björn-Rassmussen, E., Hallberg, L., & Rossander, L. (1981). Iron absorption in relation to iron status. Model proposed to express results to food iron absorption measurements. Scandinavian Journal of Haematology, 27(3), 201-8.
Magnusson B, et al. Iron Absorption in Relation to Iron Status. Model Proposed to Express Results to Food Iron Absorption Measurements. Scand J Haematol. 1981;27(3):201-8. PubMed PMID: 7313546.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Iron absorption in relation to iron status. Model proposed to express results to food iron absorption measurements. AU - Magnusson,B, AU - Björn-Rassmussen,E, AU - Hallberg,L, AU - Rossander,L, PY - 1981/9/1/pubmed PY - 1981/9/1/medline PY - 1981/9/1/entrez SP - 201 EP - 8 JF - Scandinavian journal of haematology JO - Scand J Haematol VL - 27 IS - 3 N2 - The absorption from a 3 mg dose of ferrous iron was measured in 250 male subjects. The absorption was related to the log concentration of serum ferritin in 186 subjects of whom 99 were regular blood donors (r = -0.76), and to bone marrow haemosiderin grading in 52 subjects with varying iron status. The purpose was to try and establish a percentage absorption from such a dose that is representative of subjects who are borderline iron deficient. This information is necessary for food iron absorption studies in order (1) to calculate the absorption of iron from the diet at a given iron status and (2) compare the absorption of iron from different meals studied in different groups of subjects by different investigators. The results suggest that an absorption of about 40% of a 3 mg reference dose of ferrous iron is given in a fasting state, roughly corresponds to the absorption in borderline-iron-deficient subjects. The results indicate that this 40% absorption value corresponds to a serum ferritin level of 30 microgram/l and that food iron absorption in a group of subjects should be expressed preferably as the absorption corresponding to a reference-dose absorption of 40%, or possibly a serum ferritin level of 30 microgram/l. SN - 0036-553X UR - https://www.unboundmedicine.com/medline/citation/7313546/Iron_absorption_in_relation_to_iron_status__Model_proposed_to_express_results_to_food_iron_absorption_measurements_ L2 - https://medlineplus.gov/iron.html DB - PRIME DP - Unbound Medicine ER -