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Carbon monoxide in breath in relation to smoking and carboxyhaemoglobin levels.
Thorax. 1981 May; 36(5):366-9.T

Abstract

Carboxyhaemoglobin (COHb) levels were studied in 11 249 men. The distribution among the 2613 men who smoked cigarettes was well separated from that in 6641 non-smokers (including ex-smokers). The distribution for 2005 cigar and pipe smokers was intermediate, though some of the highest COHb levels occurred in cigar smokers. Using a COHb cut-off level of 2%, 81% of cigarette smokers, 35% of cigar and pipe smokers, and 1.0% of non-smokers had raised COHb levels. In a subsidiary experiment alveolar air samples were collected from 162 smokers and 25 non-smokers using a simple breath sampling technique. Carbon monoxide concentrations in alveolar breath were highly correlated with COHb levels (r = 0.97) indicating that COHb levels can be estimated reliably by measuring the concentration of carbon monoxide in breath. Alveolar carbon monoxide measurement is thus a simple method of estimating whether a person is likely to be a smoker.

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Authors

Wald NJ
No affiliation info available
Idle M
No affiliation info available
Boreham J
No affiliation info available
Bailey A
No affiliation info available

MeSH

AdultCarbon MonoxideCarboxyhemoglobinHemoglobinsHumansMaleMiddle AgedPulmonary AlveoliRespirationSmoking

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

7314006

Citation

Wald, N J., et al. "Carbon Monoxide in Breath in Relation to Smoking and Carboxyhaemoglobin Levels." Thorax, vol. 36, no. 5, 1981, pp. 366-9.
Wald NJ, Idle M, Boreham J, et al. Carbon monoxide in breath in relation to smoking and carboxyhaemoglobin levels. Thorax. 1981;36(5):366-9.
Wald, N. J., Idle, M., Boreham, J., & Bailey, A. (1981). Carbon monoxide in breath in relation to smoking and carboxyhaemoglobin levels. Thorax, 36(5), 366-9.
Wald NJ, et al. Carbon Monoxide in Breath in Relation to Smoking and Carboxyhaemoglobin Levels. Thorax. 1981;36(5):366-9. PubMed PMID: 7314006.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Carbon monoxide in breath in relation to smoking and carboxyhaemoglobin levels. AU - Wald,N J, AU - Idle,M, AU - Boreham,J, AU - Bailey,A, PY - 1981/5/1/pubmed PY - 1981/5/1/medline PY - 1981/5/1/entrez SP - 366 EP - 9 JF - Thorax JO - Thorax VL - 36 IS - 5 N2 - Carboxyhaemoglobin (COHb) levels were studied in 11 249 men. The distribution among the 2613 men who smoked cigarettes was well separated from that in 6641 non-smokers (including ex-smokers). The distribution for 2005 cigar and pipe smokers was intermediate, though some of the highest COHb levels occurred in cigar smokers. Using a COHb cut-off level of 2%, 81% of cigarette smokers, 35% of cigar and pipe smokers, and 1.0% of non-smokers had raised COHb levels. In a subsidiary experiment alveolar air samples were collected from 162 smokers and 25 non-smokers using a simple breath sampling technique. Carbon monoxide concentrations in alveolar breath were highly correlated with COHb levels (r = 0.97) indicating that COHb levels can be estimated reliably by measuring the concentration of carbon monoxide in breath. Alveolar carbon monoxide measurement is thus a simple method of estimating whether a person is likely to be a smoker. SN - 0040-6376 UR - https://www.unboundmedicine.com/medline/citation/7314006/Carbon_monoxide_in_breath_in_relation_to_smoking_and_carboxyhaemoglobin_levels_ L2 - https://thorax.bmj.com/lookup/pmidlookup?view=long&pmid=7314006 DB - PRIME DP - Unbound Medicine ER -