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Abnormal cardiovascular reflexes in juvenile diabetics as preclinical signs of autonomic neuropathy.
G Ital Cardiol. 1981; 11(12):2139-43.GI

Abstract

The prevalence of abnormalities of cardiovascular reflexes as a marker of autonomic neuropathy was studied in a group of juvenile diabetics with long-standing disease, aged 20-58 years (mean 36). No patient had clinical evidence of autonomic failure. The study was carried out employing the most simple techniques and routine equipment. Resting heart rate, beta-to-beat variation, Valsalva ratio, systolic blood pressure in supine position and immediately after standing were measured. The results were compared with those determined in an age and sex-matched population. Beat-to-beat variation test appeared to be the most sensitive technique in detecting an impaired autonomic function (12/54 = 22.2%). Resting tachycardia was found in 10 patients and postural hypotension in 6. Only 1 patient had an abnormal Valsalva ratio associated with postural hypotension and reduced beta-to-beat variation. In agreement with previous studies our data confirm that autonomic dysfunction is frequent in asymptomatic diabetics. The methods to detect these abnormalities are easy to perform. Therefore they may be routinely used as screening tests in the diabetic population.

Authors

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Pub Type(s)

Journal Article

Language

eng

PubMed ID

7346309

Citation

Pilati, G, et al. "Abnormal Cardiovascular Reflexes in Juvenile Diabetics as Preclinical Signs of Autonomic Neuropathy." Giornale Italiano Di Cardiologia, vol. 11, no. 12, 1981, pp. 2139-43.
Pilati G, Ciavarella A, Marchesini G, et al. Abnormal cardiovascular reflexes in juvenile diabetics as preclinical signs of autonomic neuropathy. G Ital Cardiol. 1981;11(12):2139-43.
Pilati, G., Ciavarella, A., Marchesini, G., Allegro, G., Baroni, G., Vannini, P., & Pisi, E. (1981). Abnormal cardiovascular reflexes in juvenile diabetics as preclinical signs of autonomic neuropathy. Giornale Italiano Di Cardiologia, 11(12), 2139-43.
Pilati G, et al. Abnormal Cardiovascular Reflexes in Juvenile Diabetics as Preclinical Signs of Autonomic Neuropathy. G Ital Cardiol. 1981;11(12):2139-43. PubMed PMID: 7346309.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Abnormal cardiovascular reflexes in juvenile diabetics as preclinical signs of autonomic neuropathy. AU - Pilati,G, AU - Ciavarella,A, AU - Marchesini,G, AU - Allegro,G, AU - Baroni,G, AU - Vannini,P, AU - Pisi,E, PY - 1981/1/1/pubmed PY - 1981/1/1/medline PY - 1981/1/1/entrez SP - 2139 EP - 43 JF - Giornale italiano di cardiologia JO - G Ital Cardiol VL - 11 IS - 12 N2 - The prevalence of abnormalities of cardiovascular reflexes as a marker of autonomic neuropathy was studied in a group of juvenile diabetics with long-standing disease, aged 20-58 years (mean 36). No patient had clinical evidence of autonomic failure. The study was carried out employing the most simple techniques and routine equipment. Resting heart rate, beta-to-beat variation, Valsalva ratio, systolic blood pressure in supine position and immediately after standing were measured. The results were compared with those determined in an age and sex-matched population. Beat-to-beat variation test appeared to be the most sensitive technique in detecting an impaired autonomic function (12/54 = 22.2%). Resting tachycardia was found in 10 patients and postural hypotension in 6. Only 1 patient had an abnormal Valsalva ratio associated with postural hypotension and reduced beta-to-beat variation. In agreement with previous studies our data confirm that autonomic dysfunction is frequent in asymptomatic diabetics. The methods to detect these abnormalities are easy to perform. Therefore they may be routinely used as screening tests in the diabetic population. SN - 0046-5968 UR - https://www.unboundmedicine.com/medline/citation/7346309/Abnormal_cardiovascular_reflexes_in_juvenile_diabetics_as_preclinical_signs_of_autonomic_neuropathy_ DB - PRIME DP - Unbound Medicine ER -