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Toxic megacolon complicating Crohn's colitis.
Ann Surg. 1980 Jan; 191(1):75-80.AnnS

Abstract

Toxic megacolon complicating ulcerative colitis has been a well-recognized entity since its original description in 1950. The presence of toxic megacolon frequently has precluded a diagnosis of Crohn's colitis. Recent literature, however, has demonstrated that the incidence of toxic megacolon associated with Crohn's colitis (4.4-6.3%) may be higher than that in ulcerative colitis (1-2.5%). Differentiation between these two catastrophic forms of colitis is important in respect to prognosis and long-term results. Medical management of toxic megacolon may be initially successful in either type of colitis. Surgical intervention is indicated if the patient's condition does not improve within 48-72 hours. A subtotal colectomy with an ileostomy and mucous fistula is probably the treatment of choice for most of these extremely ill patients. The influence of the type of colitis on the results of subsequent management of the rectal stump remains unresolved.

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Authors

Grieco MB
No affiliation info available
Bordan DL
No affiliation info available
Geiss AC
No affiliation info available
Beil AR
No affiliation info available

MeSH

AdultColectomyColitis, UlcerativeColonCrohn DiseaseFemaleHumansMaleMegacolon, ToxicMiddle Aged

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

7352781

Citation

Grieco, M B., et al. "Toxic Megacolon Complicating Crohn's Colitis." Annals of Surgery, vol. 191, no. 1, 1980, pp. 75-80.
Grieco MB, Bordan DL, Geiss AC, et al. Toxic megacolon complicating Crohn's colitis. Ann Surg. 1980;191(1):75-80.
Grieco, M. B., Bordan, D. L., Geiss, A. C., & Beil, A. R. (1980). Toxic megacolon complicating Crohn's colitis. Annals of Surgery, 191(1), 75-80.
Grieco MB, et al. Toxic Megacolon Complicating Crohn's Colitis. Ann Surg. 1980;191(1):75-80. PubMed PMID: 7352781.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Toxic megacolon complicating Crohn's colitis. AU - Grieco,M B, AU - Bordan,D L, AU - Geiss,A C, AU - Beil,A R,Jr PY - 1980/1/1/pubmed PY - 2001/3/28/medline PY - 1980/1/1/entrez SP - 75 EP - 80 JF - Annals of surgery JO - Ann Surg VL - 191 IS - 1 N2 - Toxic megacolon complicating ulcerative colitis has been a well-recognized entity since its original description in 1950. The presence of toxic megacolon frequently has precluded a diagnosis of Crohn's colitis. Recent literature, however, has demonstrated that the incidence of toxic megacolon associated with Crohn's colitis (4.4-6.3%) may be higher than that in ulcerative colitis (1-2.5%). Differentiation between these two catastrophic forms of colitis is important in respect to prognosis and long-term results. Medical management of toxic megacolon may be initially successful in either type of colitis. Surgical intervention is indicated if the patient's condition does not improve within 48-72 hours. A subtotal colectomy with an ileostomy and mucous fistula is probably the treatment of choice for most of these extremely ill patients. The influence of the type of colitis on the results of subsequent management of the rectal stump remains unresolved. SN - 0003-4932 UR - https://www.unboundmedicine.com/medline/citation/7352781/Toxic_megacolon_complicating_Crohn's_colitis_ L2 - https://Insights.ovid.com/pubmed?pmid=7352781 DB - PRIME DP - Unbound Medicine ER -