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Wall thickness of ventricular chambers in transposition of the great arteries: surgical implications.
J Thorac Cardiovasc Surg 1980; 79(4):592-7JT

Abstract

One hundred four specimens of complete transposition of the great arteries (TGA) were studied. The free wall thickness of the left (LV-T) and right (RV-T) ventricular chambers and the left ventricular/right ventricular (LV/RV) thickness ratio for all hearts were analyzed. A control group of 63 normal hearts was also studied. Specimens of TGA were divided into four groups: (1) TGA with intact ventricular septum (TGA + IVS); (2) TGA with ventricular septal defect (TGA + VSD); (3) TGA with a large patent ductus arteriosus (TGA + PDA); (4) TGA with pulmonary stenosis (TGA + PS). In Group I, LV-T was under the 95% confidence limits for normality after 8 months of age, and in Group II, the same was true after 18 months of age. For all groups the RV-T was above the 95% confidence limits for normality from the first month of age. The LV/RV ratio was under 1 in every group. Group I showed a significant decrease in the LV/RV ratio after the neonatal period (p less than 0.005). The potential failure of the left ventricle after anatomic correction of TGA is explained by a multifactorial hypothesis. In view of the ventricular wall thickness findings, we do not recommend the anatomic correction after 8 months of age in Group I or after 18 months in Group II.

Authors

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Pub Type(s)

Journal Article

Language

eng

PubMed ID

7359938

Citation

Baño-Rodrigo, A, et al. "Wall Thickness of Ventricular Chambers in Transposition of the Great Arteries: Surgical Implications." The Journal of Thoracic and Cardiovascular Surgery, vol. 79, no. 4, 1980, pp. 592-7.
Baño-Rodrigo A, Quero-Jiménez M, Moreno-Granado F, et al. Wall thickness of ventricular chambers in transposition of the great arteries: surgical implications. J Thorac Cardiovasc Surg. 1980;79(4):592-7.
Baño-Rodrigo, A., Quero-Jiménez, M., Moreno-Granado, F., & Gamallo-Amat, C. (1980). Wall thickness of ventricular chambers in transposition of the great arteries: surgical implications. The Journal of Thoracic and Cardiovascular Surgery, 79(4), pp. 592-7.
Baño-Rodrigo A, et al. Wall Thickness of Ventricular Chambers in Transposition of the Great Arteries: Surgical Implications. J Thorac Cardiovasc Surg. 1980;79(4):592-7. PubMed PMID: 7359938.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Wall thickness of ventricular chambers in transposition of the great arteries: surgical implications. AU - Baño-Rodrigo,A, AU - Quero-Jiménez,M, AU - Moreno-Granado,F, AU - Gamallo-Amat,C, PY - 1980/4/1/pubmed PY - 1980/4/1/medline PY - 1980/4/1/entrez SP - 592 EP - 7 JF - The Journal of thoracic and cardiovascular surgery JO - J. Thorac. Cardiovasc. Surg. VL - 79 IS - 4 N2 - One hundred four specimens of complete transposition of the great arteries (TGA) were studied. The free wall thickness of the left (LV-T) and right (RV-T) ventricular chambers and the left ventricular/right ventricular (LV/RV) thickness ratio for all hearts were analyzed. A control group of 63 normal hearts was also studied. Specimens of TGA were divided into four groups: (1) TGA with intact ventricular septum (TGA + IVS); (2) TGA with ventricular septal defect (TGA + VSD); (3) TGA with a large patent ductus arteriosus (TGA + PDA); (4) TGA with pulmonary stenosis (TGA + PS). In Group I, LV-T was under the 95% confidence limits for normality after 8 months of age, and in Group II, the same was true after 18 months of age. For all groups the RV-T was above the 95% confidence limits for normality from the first month of age. The LV/RV ratio was under 1 in every group. Group I showed a significant decrease in the LV/RV ratio after the neonatal period (p less than 0.005). The potential failure of the left ventricle after anatomic correction of TGA is explained by a multifactorial hypothesis. In view of the ventricular wall thickness findings, we do not recommend the anatomic correction after 8 months of age in Group I or after 18 months in Group II. SN - 0022-5223 UR - https://www.unboundmedicine.com/medline/citation/7359938/Wall_thickness_of_ventricular_chambers_in_transposition_of_the_great_arteries:_surgical_implications_ DB - PRIME DP - Unbound Medicine ER -