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Study of the evolution of nerve damage in leprosy. Part I--Lesions of the index branch of the radial cutaneous nerve in early leprosy.
Lepr India. 1980 Jan; 52(1):5-18.LI

Abstract

A total of six index finger branch of the radial cutaneous (IRC) nerves from three BL, two BB and one BT cases of leprosy, with less than 6 months history of disease were subjected for nerve conduction velocity (NCV) studies followed by biopsy. The biopsy was divided into three parts and subjected for light microscopy quantitative histology, electron-microscopy and fibre tease studies. The nerves revealed a slight reduction in NCV and a varying degree of segmental demyelination ranging from 10% to 35%. The earliest changes observed were the thickening and proliferation of Schwann cell processes of the unmyelinated fibres and degeneration of their axons regardless of the type of leprosy.

Authors

Shetty VP
No affiliation info available
Mehta LN
No affiliation info available
Irani PF
No affiliation info available
Antia NH
No affiliation info available

MeSH

AdolescentAdultChildFemaleFingersHumansLeprosyMaleMiddle AgedNerve DegenerationNerve FibersNeural ConductionRadial NerveSchwann CellsSkinTime Factors

Pub Type(s)

Journal Article

Language

eng

PubMed ID

7382434

Citation

Shetty, V P., et al. "Study of the Evolution of Nerve Damage in Leprosy. Part I--Lesions of the Index Branch of the Radial Cutaneous Nerve in Early Leprosy." Leprosy in India, vol. 52, no. 1, 1980, pp. 5-18.
Shetty VP, Mehta LN, Irani PF, et al. Study of the evolution of nerve damage in leprosy. Part I--Lesions of the index branch of the radial cutaneous nerve in early leprosy. Lepr India. 1980;52(1):5-18.
Shetty, V. P., Mehta, L. N., Irani, P. F., & Antia, N. H. (1980). Study of the evolution of nerve damage in leprosy. Part I--Lesions of the index branch of the radial cutaneous nerve in early leprosy. Leprosy in India, 52(1), 5-18.
Shetty VP, et al. Study of the Evolution of Nerve Damage in Leprosy. Part I--Lesions of the Index Branch of the Radial Cutaneous Nerve in Early Leprosy. Lepr India. 1980;52(1):5-18. PubMed PMID: 7382434.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Study of the evolution of nerve damage in leprosy. Part I--Lesions of the index branch of the radial cutaneous nerve in early leprosy. AU - Shetty,V P, AU - Mehta,L N, AU - Irani,P F, AU - Antia,N H, PY - 1980/1/1/pubmed PY - 1980/1/1/medline PY - 1980/1/1/entrez SP - 5 EP - 18 JF - Leprosy in India JO - Lepr India VL - 52 IS - 1 N2 - A total of six index finger branch of the radial cutaneous (IRC) nerves from three BL, two BB and one BT cases of leprosy, with less than 6 months history of disease were subjected for nerve conduction velocity (NCV) studies followed by biopsy. The biopsy was divided into three parts and subjected for light microscopy quantitative histology, electron-microscopy and fibre tease studies. The nerves revealed a slight reduction in NCV and a varying degree of segmental demyelination ranging from 10% to 35%. The earliest changes observed were the thickening and proliferation of Schwann cell processes of the unmyelinated fibres and degeneration of their axons regardless of the type of leprosy. SN - 0024-1024 UR - https://www.unboundmedicine.com/medline/citation/7382434/Study_of_the_evolution_of_nerve_damage_in_leprosy__Part_I__Lesions_of_the_index_branch_of_the_radial_cutaneous_nerve_in_early_leprosy_ L2 - https://medlineplus.gov/mycobacterialinfections.html DB - PRIME DP - Unbound Medicine ER -