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Failure of piracetam to facilitate acquisition or retention in younger or older rats.
Exp Aging Res. 1980 Apr; 6(2):175-80.EA

Abstract

The performance of Long-Evans hooded rats of two age groups (450 and 75 days) was observed in open field activity, one-way active avoidance, and passive avoidance conditioning. One-half of the subjects in each group were administered 100 mg/kg of piracetam two hours prior to all testing trials. Younger rats required fewer acquisition trials to reach active avoidance criterion and made more active avoidances on 7-day retention tests than did older rats. Thus, younger rats performed better on both acquisition and retention of active and passive avoidance conditioning. Piracetam did not produce significant behavioral changes in any of the groups on any of the tasks. Neither age nor piracetam was shown to affect activity.

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Authors

Means LW
No affiliation info available
Franklin RD
No affiliation info available
Cliett CE
No affiliation info available

MeSH

Age FactorsAnimalsAvoidance LearningMaleMemoryPiracetamPyrrolidinonesRatsRetention, Psychology

Pub Type(s)

Journal Article

Language

eng

PubMed ID

7389786

Citation

Means, L W., et al. "Failure of Piracetam to Facilitate Acquisition or Retention in Younger or Older Rats." Experimental Aging Research, vol. 6, no. 2, 1980, pp. 175-80.
Means LW, Franklin RD, Cliett CE. Failure of piracetam to facilitate acquisition or retention in younger or older rats. Exp Aging Res. 1980;6(2):175-80.
Means, L. W., Franklin, R. D., & Cliett, C. E. (1980). Failure of piracetam to facilitate acquisition or retention in younger or older rats. Experimental Aging Research, 6(2), 175-80.
Means LW, Franklin RD, Cliett CE. Failure of Piracetam to Facilitate Acquisition or Retention in Younger or Older Rats. Exp Aging Res. 1980;6(2):175-80. PubMed PMID: 7389786.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Failure of piracetam to facilitate acquisition or retention in younger or older rats. AU - Means,L W, AU - Franklin,R D, AU - Cliett,C E, PY - 1980/4/1/pubmed PY - 1980/4/1/medline PY - 1980/4/1/entrez SP - 175 EP - 80 JF - Experimental aging research JO - Exp Aging Res VL - 6 IS - 2 N2 - The performance of Long-Evans hooded rats of two age groups (450 and 75 days) was observed in open field activity, one-way active avoidance, and passive avoidance conditioning. One-half of the subjects in each group were administered 100 mg/kg of piracetam two hours prior to all testing trials. Younger rats required fewer acquisition trials to reach active avoidance criterion and made more active avoidances on 7-day retention tests than did older rats. Thus, younger rats performed better on both acquisition and retention of active and passive avoidance conditioning. Piracetam did not produce significant behavioral changes in any of the groups on any of the tasks. Neither age nor piracetam was shown to affect activity. SN - 0361-073X UR - https://www.unboundmedicine.com/medline/citation/7389786/Failure_of_piracetam_to_facilitate_acquisition_or_retention_in_younger_or_older_rats_ L2 - https://www.tandfonline.com/doi/full/10.1080/03610738008258354 DB - PRIME DP - Unbound Medicine ER -