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Reduction of urine oxalate during long-term thiazide therapy in patients with calcium urolithiasis.
Invest Urol. 1980 Sep; 18(2):170-3.IU

Abstract

We measured urinary oxalate by the method of Hallson and Rose before and during long-term thiazide therapy in 49 patients with recurrent urolithiasis. Urinary oxalate excretion in normal men and women on their usual diets was 38.8 +/- 10.3 mg per day (mean +/- SD) and in patients with calcific renal calculi was 45.9 +/- 14.3 mg per day. Hydrochlorothiazide produced a significant decrease in urinary oxalate excretion in patients treated for more than 12 months (33 +/- 10.6 mg per day). We believe that the thiazide-induced reduction of urinary oxalate excretion is related to reduced intestinal calcium absorption which has been shown during chronic thiazide therapy and may not be evident until 12 or more months of thiazide administration.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

7410033

Citation

Cohanim, M, and E R. Yendt. "Reduction of Urine Oxalate During Long-term Thiazide Therapy in Patients With Calcium Urolithiasis." Investigative Urology, vol. 18, no. 2, 1980, pp. 170-3.
Cohanim M, Yendt ER. Reduction of urine oxalate during long-term thiazide therapy in patients with calcium urolithiasis. Invest Urol. 1980;18(2):170-3.
Cohanim, M., & Yendt, E. R. (1980). Reduction of urine oxalate during long-term thiazide therapy in patients with calcium urolithiasis. Investigative Urology, 18(2), 170-3.
Cohanim M, Yendt ER. Reduction of Urine Oxalate During Long-term Thiazide Therapy in Patients With Calcium Urolithiasis. Invest Urol. 1980;18(2):170-3. PubMed PMID: 7410033.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Reduction of urine oxalate during long-term thiazide therapy in patients with calcium urolithiasis. AU - Cohanim,M, AU - Yendt,E R, PY - 1980/9/1/pubmed PY - 1980/9/1/medline PY - 1980/9/1/entrez SP - 170 EP - 3 JF - Investigative urology JO - Invest Urol VL - 18 IS - 2 N2 - We measured urinary oxalate by the method of Hallson and Rose before and during long-term thiazide therapy in 49 patients with recurrent urolithiasis. Urinary oxalate excretion in normal men and women on their usual diets was 38.8 +/- 10.3 mg per day (mean +/- SD) and in patients with calcific renal calculi was 45.9 +/- 14.3 mg per day. Hydrochlorothiazide produced a significant decrease in urinary oxalate excretion in patients treated for more than 12 months (33 +/- 10.6 mg per day). We believe that the thiazide-induced reduction of urinary oxalate excretion is related to reduced intestinal calcium absorption which has been shown during chronic thiazide therapy and may not be evident until 12 or more months of thiazide administration. SN - 0021-0005 UR - https://www.unboundmedicine.com/medline/citation/7410033/Reduction_of_urine_oxalate_during_long_term_thiazide_therapy_in_patients_with_calcium_urolithiasis_ DB - PRIME DP - Unbound Medicine ER -