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Characterization of mutagenic principles and carcinogenicity of dill weed and seeds.

Abstract

Among the various kinds of spices tested, the aqueous extracts of dill weed from Anethum graveolens L. and dill seeds from A. sowa D.C. (Umbelliferae), exhibited a mutagenicity to Salmonella typhimurium, strains TA98 and TA100. The aqueous methanol extracts were fractionated by the mutation assay using the strain TA98 with S-9 Mix. Isorhamnetin 3-sulfate (persicarin) and quercetin 3-sulfate were characterized as the mutagenic principles. Carcinogenicity was not observed for dill weed and seeds when the diets containing these in 33% were administered for 450 and 410 days, respectively, to the inbred strain ACI rats.

Authors

, , , , , ,

Source

Journal of pharmacobio-dynamics 3:5 1980 May pg 236-44

MeSH

Animals
Carcinogens
Condiments
Female
Flavonoids
Hydrolysis
Male
Mutagenicity Tests
Mutagens
Quercetin
Rats
Seeds

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

7411385