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Plasma high-density lipoprotein cholesterol comparisons in black and white populations. The Lipid Research Clinics Program Prevalence Study.
Circulation 1980; 62(4 Pt 2):IV99-107Circ

Abstract

High-density lipoprotein (HDL) cholesterol distributions were compared among 191 black and 1341 white males and 233 black and 1088 white females, ages 5-44 years, examined in five of the Lipid Research Clinic (LRC) population-based surveys. Mean HDL cholesterol was higher in blacks than whites in each 5-year age group for males and in seven of the eight age groups for females. The black-white mean HDL cholesterol difference was greater for males than females at each age studied. Mean HDL cholesterol was 4.8 mg/dl higher in black than white males ages 5-19 years, after statistical adjustment for age, Quetelet index and plasma total cholesterol differences between blacks and whites (p < 0.001); mean HDL cholesterol was 9.5 mg/dl higher in black than white adult males ages 20-44 years. Adjustment for levels of plasma triglyceride, which were lower in blacks than whites, reduced but did not eliminate the magnitude of the statistical significance in black-white differences: The adjusted means were 2.9 mg/dl higher in black children and 7.9 mg/dl higher in black adults. The finding of higher levels of HDL cholesterol in black males persisted after additional adjustment for alcohol consumption, smoking and educational levels. Adult U.S. black males have lower and black females have higher coronary heart disease mortality rates than their white peers. The magnitude of the black-white difference in HDL cholesterol for males in the LRC studies was within the range associated with coronary heart disease incidence reported in other studies.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

7418150

Citation

Tyroler, H A., et al. "Plasma High-density Lipoprotein Cholesterol Comparisons in Black and White Populations. the Lipid Research Clinics Program Prevalence Study." Circulation, vol. 62, no. 4 Pt 2, 1980, pp. IV99-107.
Tyroler HA, Glueck CJ, Christensen B, et al. Plasma high-density lipoprotein cholesterol comparisons in black and white populations. The Lipid Research Clinics Program Prevalence Study. Circulation. 1980;62(4 Pt 2):IV99-107.
Tyroler, H. A., Glueck, C. J., Christensen, B., & Kwiterovich, P. O. (1980). Plasma high-density lipoprotein cholesterol comparisons in black and white populations. The Lipid Research Clinics Program Prevalence Study. Circulation, 62(4 Pt 2), pp. IV99-107.
Tyroler HA, et al. Plasma High-density Lipoprotein Cholesterol Comparisons in Black and White Populations. the Lipid Research Clinics Program Prevalence Study. Circulation. 1980;62(4 Pt 2):IV99-107. PubMed PMID: 7418150.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Plasma high-density lipoprotein cholesterol comparisons in black and white populations. The Lipid Research Clinics Program Prevalence Study. AU - Tyroler,H A, AU - Glueck,C J, AU - Christensen,B, AU - Kwiterovich,P O,Jr PY - 1980/11/1/pubmed PY - 2001/3/28/medline PY - 1980/11/1/entrez SP - IV99 EP - 107 JF - Circulation JO - Circulation VL - 62 IS - 4 Pt 2 N2 - High-density lipoprotein (HDL) cholesterol distributions were compared among 191 black and 1341 white males and 233 black and 1088 white females, ages 5-44 years, examined in five of the Lipid Research Clinic (LRC) population-based surveys. Mean HDL cholesterol was higher in blacks than whites in each 5-year age group for males and in seven of the eight age groups for females. The black-white mean HDL cholesterol difference was greater for males than females at each age studied. Mean HDL cholesterol was 4.8 mg/dl higher in black than white males ages 5-19 years, after statistical adjustment for age, Quetelet index and plasma total cholesterol differences between blacks and whites (p < 0.001); mean HDL cholesterol was 9.5 mg/dl higher in black than white adult males ages 20-44 years. Adjustment for levels of plasma triglyceride, which were lower in blacks than whites, reduced but did not eliminate the magnitude of the statistical significance in black-white differences: The adjusted means were 2.9 mg/dl higher in black children and 7.9 mg/dl higher in black adults. The finding of higher levels of HDL cholesterol in black males persisted after additional adjustment for alcohol consumption, smoking and educational levels. Adult U.S. black males have lower and black females have higher coronary heart disease mortality rates than their white peers. The magnitude of the black-white difference in HDL cholesterol for males in the LRC studies was within the range associated with coronary heart disease incidence reported in other studies. SN - 0009-7322 UR - https://www.unboundmedicine.com/medline/citation/7418150/Plasma_high_density_lipoprotein_cholesterol_comparisons_in_black_and_white_populations__The_Lipid_Research_Clinics_Program_Prevalence_Study_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=linkout&amp;SEARCH=7418150.ui DB - PRIME DP - Unbound Medicine ER -