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[Enzymes of citrate and isocitrate conversion in the heart and skeletal muscle mitochondria of embryos and adult rabbits].
Vopr Med Khim. 1980 Sep-Oct; 26(5):694-8.VM

Abstract

Activities of citrate synthase, aconitase, NAD- and NADP-dependent isocitrate dehydrogenases were studied in mitochondria of heart and skeletal muscles of embryos and adult rabbits. Activity of these enzymes was some times lower in embryonal skeletal muscles as compared with the muscles of adult animals. Differences in activities of citrate synthase, aconitase and NADP-dependent isocitrate dehydrogenase were unsignificant in heart muscles of embryos and adult animals. Activity of NAD-dependent isocitrate dehydrogenase was distinctly higher in embryonal heart than in adult rabbits. The kinetic parameters enabled to conclude that in vitro regulation of NAD-dependent oxidation of isocitrate by substrate and activator ADP, characteristic for the enzyme from tissues of adult animals, was also found in embryos.

Authors

Sharkova EV
No affiliation info available

MeSH

Aconitate HydrataseAnimalsCitrate (si)-SynthaseCitratesEmbryo, MammalianEnzyme ActivationIsocitrate DehydrogenaseIsocitratesMitochondria, HeartMitochondria, MuscleRabbits

Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

rus

PubMed ID

7423888

Citation

Sharkova, E V.. "[Enzymes of Citrate and Isocitrate Conversion in the Heart and Skeletal Muscle Mitochondria of Embryos and Adult Rabbits]." Voprosy Meditsinskoi Khimii, vol. 26, no. 5, 1980, pp. 694-8.
Sharkova EV. [Enzymes of citrate and isocitrate conversion in the heart and skeletal muscle mitochondria of embryos and adult rabbits]. Vopr Med Khim. 1980;26(5):694-8.
Sharkova, E. V. (1980). [Enzymes of citrate and isocitrate conversion in the heart and skeletal muscle mitochondria of embryos and adult rabbits]. Voprosy Meditsinskoi Khimii, 26(5), 694-8.
Sharkova EV. [Enzymes of Citrate and Isocitrate Conversion in the Heart and Skeletal Muscle Mitochondria of Embryos and Adult Rabbits]. Vopr Med Khim. 1980 Sep-Oct;26(5):694-8. PubMed PMID: 7423888.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Enzymes of citrate and isocitrate conversion in the heart and skeletal muscle mitochondria of embryos and adult rabbits]. A1 - Sharkova,E V, PY - 1980/9/1/pubmed PY - 1980/9/1/medline PY - 1980/9/1/entrez SP - 694 EP - 8 JF - Voprosy meditsinskoi khimii JO - Vopr Med Khim VL - 26 IS - 5 N2 - Activities of citrate synthase, aconitase, NAD- and NADP-dependent isocitrate dehydrogenases were studied in mitochondria of heart and skeletal muscles of embryos and adult rabbits. Activity of these enzymes was some times lower in embryonal skeletal muscles as compared with the muscles of adult animals. Differences in activities of citrate synthase, aconitase and NADP-dependent isocitrate dehydrogenase were unsignificant in heart muscles of embryos and adult animals. Activity of NAD-dependent isocitrate dehydrogenase was distinctly higher in embryonal heart than in adult rabbits. The kinetic parameters enabled to conclude that in vitro regulation of NAD-dependent oxidation of isocitrate by substrate and activator ADP, characteristic for the enzyme from tissues of adult animals, was also found in embryos. SN - 0042-8809 UR - https://www.unboundmedicine.com/medline/citation/7423888/[Enzymes_of_citrate_and_isocitrate_conversion_in_the_heart_and_skeletal_muscle_mitochondria_of_embryos_and_adult_rabbits]_ DB - PRIME DP - Unbound Medicine ER -