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Comparison of bran, ispaghula, and lactulose on colon function in diverticular disease.
Gut. 1978 Dec; 19(12):1144-7.Gut

Abstract

Bran, ispaghula (Fybogel), and lactulose were given to three groups of patients with diverticular disease for four weeks. Faecal weights, bile acids, fat and electrolytes, transit time, and colonic motility were estimated before and after treatment. Stool weight increased, notably with Fybogel. Cereal bran had the greatest effect on the transit time, reducing it significantly. There were no changes in faecal bile acids, fat or electrolytes. Coarse bran reduced colonic motility and the number of high pressure waves after food; Fybogel increased the basal pressure and was without effect on the food-stimulated pressures; whereas lactulose influenced neither. All agents paradoxically equally alleviated symptoms.

Authors

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Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

744500

Citation

Eastwood, M A., et al. "Comparison of Bran, Ispaghula, and Lactulose On Colon Function in Diverticular Disease." Gut, vol. 19, no. 12, 1978, pp. 1144-7.
Eastwood MA, Smith AN, Brydon WG, et al. Comparison of bran, ispaghula, and lactulose on colon function in diverticular disease. Gut. 1978;19(12):1144-7.
Eastwood, M. A., Smith, A. N., Brydon, W. G., & Pritchard, J. (1978). Comparison of bran, ispaghula, and lactulose on colon function in diverticular disease. Gut, 19(12), 1144-7.
Eastwood MA, et al. Comparison of Bran, Ispaghula, and Lactulose On Colon Function in Diverticular Disease. Gut. 1978;19(12):1144-7. PubMed PMID: 744500.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of bran, ispaghula, and lactulose on colon function in diverticular disease. AU - Eastwood,M A, AU - Smith,A N, AU - Brydon,W G, AU - Pritchard,J, PY - 1978/12/1/pubmed PY - 1978/12/1/medline PY - 1978/12/1/entrez SP - 1144 EP - 7 JF - Gut JO - Gut VL - 19 IS - 12 N2 - Bran, ispaghula (Fybogel), and lactulose were given to three groups of patients with diverticular disease for four weeks. Faecal weights, bile acids, fat and electrolytes, transit time, and colonic motility were estimated before and after treatment. Stool weight increased, notably with Fybogel. Cereal bran had the greatest effect on the transit time, reducing it significantly. There were no changes in faecal bile acids, fat or electrolytes. Coarse bran reduced colonic motility and the number of high pressure waves after food; Fybogel increased the basal pressure and was without effect on the food-stimulated pressures; whereas lactulose influenced neither. All agents paradoxically equally alleviated symptoms. SN - 0017-5749 UR - https://www.unboundmedicine.com/medline/citation/744500/Comparison_of_bran_ispaghula_and_lactulose_on_colon_function_in_diverticular_disease_ L2 - https://gut.bmj.com/lookup/pmidlookup?view=long&pmid=744500 DB - PRIME DP - Unbound Medicine ER -