Fibrogenic potential of slags used as substitutes for sand in abrasive blasting operations.Am Ind Hyg Assoc J. 1980 Nov; 41(11):836-42.AI
Abstract
The fibrogenic potentials of coal and copper slags used as substitutes for silica sand in abrasive blasting operations were assessed in rats. The test animals were given a single pulmonary intralobar instillation of 20 mg of test material and were sacrificed 10 months after dosing. Pulmonary fibrosis was seen in the coal slag-treated rats while no fibrosis was seen in the copper slag-treated animals. Granulomas were seen in the lungs from all treatment groups. The results of the study emphasize the need for bioassay of silica sand replacements for fibrogenic potential in spite of the low free silica contents of these materials.
Pub Type(s)
Journal Article
Language
eng
PubMed ID
7457375
Citation
Mackay, G R., et al. "Fibrogenic Potential of Slags Used as Substitutes for Sand in Abrasive Blasting Operations." American Industrial Hygiene Association Journal, vol. 41, no. 11, 1980, pp. 836-42.
Mackay GR, Stettler LE, Kommineni C, et al. Fibrogenic potential of slags used as substitutes for sand in abrasive blasting operations. Am Ind Hyg Assoc J. 1980;41(11):836-42.
Mackay, G. R., Stettler, L. E., Kommineni, C., & Donaldson, H. M. (1980). Fibrogenic potential of slags used as substitutes for sand in abrasive blasting operations. American Industrial Hygiene Association Journal, 41(11), 836-42.
Mackay GR, et al. Fibrogenic Potential of Slags Used as Substitutes for Sand in Abrasive Blasting Operations. Am Ind Hyg Assoc J. 1980;41(11):836-42. PubMed PMID: 7457375.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Fibrogenic potential of slags used as substitutes for sand in abrasive blasting operations.
AU - Mackay,G R,
AU - Stettler,L E,
AU - Kommineni,C,
AU - Donaldson,H M,
PY - 1980/11/1/pubmed
PY - 1980/11/1/medline
PY - 1980/11/1/entrez
SP - 836
EP - 42
JF - American Industrial Hygiene Association journal
JO - Am Ind Hyg Assoc J
VL - 41
IS - 11
N2 - The fibrogenic potentials of coal and copper slags used as substitutes for silica sand in abrasive blasting operations were assessed in rats. The test animals were given a single pulmonary intralobar instillation of 20 mg of test material and were sacrificed 10 months after dosing. Pulmonary fibrosis was seen in the coal slag-treated rats while no fibrosis was seen in the copper slag-treated animals. Granulomas were seen in the lungs from all treatment groups. The results of the study emphasize the need for bioassay of silica sand replacements for fibrogenic potential in spite of the low free silica contents of these materials.
SN - 0002-8894
UR - https://www.unboundmedicine.com/medline/citation/7457375/Fibrogenic_potential_of_slags_used_as_substitutes_for_sand_in_abrasive_blasting_operations_
L2 - https://medlineplus.gov/lungdiseases.html
DB - PRIME
DP - Unbound Medicine
ER -