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A distinctive variant of pernio. Clinical and histopathologic study of nine cases.
Arch Dermatol. 1981 Jan; 117(1):26-8.AD

Abstract

We describe here nine women who had similar distinctive clinical features that consisted of painful red-to-purple macules, papules, and plaques on the digits, predominantly on the toes. All patients reported that exposure to cold had preceded their symptoms. Histologic study demonstrated a lymphocytic vasculitis, characterized by lymphocytes infiltrating the walls of blood vessels in eight (88%) of nine lesions. This pattern of inflammation is different from the perivascular lymphocytic infiltrate that is common to lupus erythematosus, erythema multiforme, lymphocytic infiltration of the skin (Jessner), and drug eruptions. It also serves to distinguish the disorder from other clinical conditions resembling it, such as cellulitis, herpes simplex infection, and disseminated gonococcemia. To the best of our knowledge, this lymphocytic vasculitis has not been previously described as occurring in pernio. We believe the unique disorder that we are reporting is a common, but infrequently recognized, variant of pernio.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

7458375

Citation

Herman, E W., et al. "A Distinctive Variant of Pernio. Clinical and Histopathologic Study of Nine Cases." Archives of Dermatology, vol. 117, no. 1, 1981, pp. 26-8.
Herman EW, Kezis JS, Silvers DN. A distinctive variant of pernio. Clinical and histopathologic study of nine cases. Arch Dermatol. 1981;117(1):26-8.
Herman, E. W., Kezis, J. S., & Silvers, D. N. (1981). A distinctive variant of pernio. Clinical and histopathologic study of nine cases. Archives of Dermatology, 117(1), 26-8.
Herman EW, Kezis JS, Silvers DN. A Distinctive Variant of Pernio. Clinical and Histopathologic Study of Nine Cases. Arch Dermatol. 1981;117(1):26-8. PubMed PMID: 7458375.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A distinctive variant of pernio. Clinical and histopathologic study of nine cases. AU - Herman,E W, AU - Kezis,J S, AU - Silvers,D N, PY - 1981/1/1/pubmed PY - 1981/1/1/medline PY - 1981/1/1/entrez SP - 26 EP - 8 JF - Archives of dermatology JO - Arch Dermatol VL - 117 IS - 1 N2 - We describe here nine women who had similar distinctive clinical features that consisted of painful red-to-purple macules, papules, and plaques on the digits, predominantly on the toes. All patients reported that exposure to cold had preceded their symptoms. Histologic study demonstrated a lymphocytic vasculitis, characterized by lymphocytes infiltrating the walls of blood vessels in eight (88%) of nine lesions. This pattern of inflammation is different from the perivascular lymphocytic infiltrate that is common to lupus erythematosus, erythema multiforme, lymphocytic infiltration of the skin (Jessner), and drug eruptions. It also serves to distinguish the disorder from other clinical conditions resembling it, such as cellulitis, herpes simplex infection, and disseminated gonococcemia. To the best of our knowledge, this lymphocytic vasculitis has not been previously described as occurring in pernio. We believe the unique disorder that we are reporting is a common, but infrequently recognized, variant of pernio. SN - 0003-987X UR - https://www.unboundmedicine.com/medline/citation/7458375/A_distinctive_variant_of_pernio._Clinical_and_histopathologic_study_of_nine_cases L2 - https://jamanetwork.com/journals/jamadermatology/fullarticle/vol/117/pg/26 DB - PRIME DP - Unbound Medicine ER -