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Oral contraceptive use and early abortion as risk factors for breast cancer in young women.
Br J Cancer. 1981 Jan; 43(1):72-6.BJ

Abstract

A case-control study was conducted in Los Angeles County, California, of 163 very young breast-cancer cases (all aged 32 or less at diagnosis) to investigate the role, if any, of oral contraceptives (OC) in the development of the disease. OC use before first full-term pregnancy (FFTP) was associated with an elevated risk, which increased with duration of OC use (relative risk approximately 2.2 at 6 years of use, P < 0.01). This increased risk could not be explained by other risk factors. OC use after FFTP was not associated with any change in risk. A first-trimester abortion before FFTP, whether spontaneous or induced, was associated with a 2.4-fold increase in breast-cancer risk (P < 0.005).

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

7459241

Citation

Pike, M C., et al. "Oral Contraceptive Use and Early Abortion as Risk Factors for Breast Cancer in Young Women." British Journal of Cancer, vol. 43, no. 1, 1981, pp. 72-6.
Pike MC, Henderson BE, Casagrande JT, et al. Oral contraceptive use and early abortion as risk factors for breast cancer in young women. Br J Cancer. 1981;43(1):72-6.
Pike, M. C., Henderson, B. E., Casagrande, J. T., Rosario, I., & Gray, G. E. (1981). Oral contraceptive use and early abortion as risk factors for breast cancer in young women. British Journal of Cancer, 43(1), 72-6.
Pike MC, et al. Oral Contraceptive Use and Early Abortion as Risk Factors for Breast Cancer in Young Women. Br J Cancer. 1981;43(1):72-6. PubMed PMID: 7459241.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Oral contraceptive use and early abortion as risk factors for breast cancer in young women. AU - Pike,M C, AU - Henderson,B E, AU - Casagrande,J T, AU - Rosario,I, AU - Gray,G E, PY - 1981/1/1/pubmed PY - 1981/1/1/medline PY - 1981/1/1/entrez KW - Abortion, Induced KW - Americas KW - Breast Cancer KW - California KW - Cancer KW - Comparative Studies KW - Developed Countries KW - Diseases KW - Neoplasms KW - North America KW - Northern America KW - Oral Contraceptives KW - Pregnancy KW - Research Methodology KW - Studies KW - United States SP - 72 EP - 6 JF - British journal of cancer JO - Br. J. Cancer VL - 43 IS - 1 N2 - A case-control study was conducted in Los Angeles County, California, of 163 very young breast-cancer cases (all aged 32 or less at diagnosis) to investigate the role, if any, of oral contraceptives (OC) in the development of the disease. OC use before first full-term pregnancy (FFTP) was associated with an elevated risk, which increased with duration of OC use (relative risk approximately 2.2 at 6 years of use, P < 0.01). This increased risk could not be explained by other risk factors. OC use after FFTP was not associated with any change in risk. A first-trimester abortion before FFTP, whether spontaneous or induced, was associated with a 2.4-fold increase in breast-cancer risk (P < 0.005). SN - 0007-0920 UR - https://www.unboundmedicine.com/medline/citation/7459241/Oral_contraceptive_use_and_early_abortion_as_risk_factors_for_breast_cancer_in_young_women_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/7459241/ DB - PRIME DP - Unbound Medicine ER -