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[Liver cirrhosis and chronic hepatic porphyria].
Z Gastroenterol 1993; 31 Suppl 2:114-5ZG

Abstract

Chronic hepatic porphyrias (CHP) are associated with different degrees of liver damage. They range from minimal histological changes to cirrhosis and primary liver carcinomas. Forty patients with early stages of porphyrias were compared to 85 patients with clinically manifest porphyrias, Porphyria cutanea tarda. This comparison resulted in the fact that cirrhosis occurred more often in early (or latent) stages (65%) than in PCT (31%) confirmed by laparoscopy. Thus the severity of the liver disease does not depend on the duration and intensity of cutaneous symptoms or pathobiochemical syndromes but they more often depend on the long-term influence of so-called trigger factors, among them above all alcohol and iron overloading. We conclude that the proof of latent CHP has an index function for severer liver damage.

Authors+Show Affiliations

III. Medizinische Klinik, Krankenhaus Dresden-Friedrichstadt, Dresden.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

ger

PubMed ID

7483690

Citation

Pätzold, K, et al. "[Liver Cirrhosis and Chronic Hepatic Porphyria]." Zeitschrift Fur Gastroenterologie, vol. 31 Suppl 2, 1993, pp. 114-5.
Pätzold K, Hahn L, Lohmann J, et al. [Liver cirrhosis and chronic hepatic porphyria]. Z Gastroenterol. 1993;31 Suppl 2:114-5.
Pätzold, K., Hahn, L., Lohmann, J., & Porst, H. (1993). [Liver cirrhosis and chronic hepatic porphyria]. Zeitschrift Fur Gastroenterologie, 31 Suppl 2, pp. 114-5.
Pätzold K, et al. [Liver Cirrhosis and Chronic Hepatic Porphyria]. Z Gastroenterol. 1993;31 Suppl 2:114-5. PubMed PMID: 7483690.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Liver cirrhosis and chronic hepatic porphyria]. AU - Pätzold,K, AU - Hahn,L, AU - Lohmann,J, AU - Porst,H, PY - 1993/2/1/pubmed PY - 1993/2/1/medline PY - 1993/2/1/entrez SP - 114 EP - 5 JF - Zeitschrift fur Gastroenterologie JO - Z Gastroenterol VL - 31 Suppl 2 N2 - Chronic hepatic porphyrias (CHP) are associated with different degrees of liver damage. They range from minimal histological changes to cirrhosis and primary liver carcinomas. Forty patients with early stages of porphyrias were compared to 85 patients with clinically manifest porphyrias, Porphyria cutanea tarda. This comparison resulted in the fact that cirrhosis occurred more often in early (or latent) stages (65%) than in PCT (31%) confirmed by laparoscopy. Thus the severity of the liver disease does not depend on the duration and intensity of cutaneous symptoms or pathobiochemical syndromes but they more often depend on the long-term influence of so-called trigger factors, among them above all alcohol and iron overloading. We conclude that the proof of latent CHP has an index function for severer liver damage. SN - 0044-2771 UR - https://www.unboundmedicine.com/medline/citation/7483690/[Liver_cirrhosis_and_chronic_hepatic_porphyria]_ L2 - http://www.diseaseinfosearch.org/result/5879 DB - PRIME DP - Unbound Medicine ER -