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[Subcutaneous sumatriptan in the treatment of migraine attacks. An analysis of its long term efficaciousness and tolerance].
Rev Neurol. 1995 Jul-Aug; 23(122):752-5.RN

Abstract

We present the results of treatment with subcutaneous sumatriptan in migraine attacks. The study comprised forty-two patients suffering from migraine both with and without aura, with migraine attacks not susceptible to analgesics, non-steroid anti-inflammatory drugs (NSAID), ergotics or else intolerance to the same. Two groups were independently analyzed, one consisting of ten patients who had menstrual migraine continually for twelve months, the other consisting of thirty-two patients suffering from migraine with and without aura for six months. We assessed the effectiveness of the drug (reduction in the intensity and duration of the attack, action, speed, recurrence) and tolerance (adverse effects). The effectiveness of sumatriptan in relieving headache was 75.9% (80% in the case of the menstrual migraine group and 71.8% in the case of the migraine with and without aura group). This effectiveness was maintained in a similar fashion by analyzing independently the first and last months of treatment. Adverse effects were noted in 38.7% of patients treated (40% for the menstrual migraine group, 37.5% for those with migraine with and without aura). The most frequent effects were pain at the point of injection, a feeling of general tiredness, nausea and a sensation of tension in the neck or chest. These effects were largely slight and short lived. No serious adverse effects were reported. A long term analysis carried out on the menstrual migraine group shows the efficacy of sumatriptan is kept up, with improved tolerance of the drug and a decrease in the number of negative side effects noted.(

ABSTRACT

TRUNCATED AT 250 WORDS)

Authors+Show Affiliations

Servicio de Neurología, Hospital General de Galicia Clínico Universitario, Santiago de Compostela.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

spa

PubMed ID

7497233

Citation

Leira, R, et al. "[Subcutaneous Sumatriptan in the Treatment of Migraine Attacks. an Analysis of Its Long Term Efficaciousness and Tolerance]." Revista De Neurologia, vol. 23, no. 122, 1995, pp. 752-5.
Leira R, Suárez C, Castillo J, et al. [Subcutaneous sumatriptan in the treatment of migraine attacks. An analysis of its long term efficaciousness and tolerance]. Rev Neurol. 1995;23(122):752-5.
Leira, R., Suárez, C., Castillo, J., Lema, M., & Noya, M. (1995). [Subcutaneous sumatriptan in the treatment of migraine attacks. An analysis of its long term efficaciousness and tolerance]. Revista De Neurologia, 23(122), 752-5.
Leira R, et al. [Subcutaneous Sumatriptan in the Treatment of Migraine Attacks. an Analysis of Its Long Term Efficaciousness and Tolerance]. Rev Neurol. 1995 Jul-Aug;23(122):752-5. PubMed PMID: 7497233.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Subcutaneous sumatriptan in the treatment of migraine attacks. An analysis of its long term efficaciousness and tolerance]. AU - Leira,R, AU - Suárez,C, AU - Castillo,J, AU - Lema,M, AU - Noya,M, PY - 1995/7/1/pubmed PY - 1995/7/1/medline PY - 1995/7/1/entrez SP - 752 EP - 5 JF - Revista de neurologia JO - Rev Neurol VL - 23 IS - 122 N2 - We present the results of treatment with subcutaneous sumatriptan in migraine attacks. The study comprised forty-two patients suffering from migraine both with and without aura, with migraine attacks not susceptible to analgesics, non-steroid anti-inflammatory drugs (NSAID), ergotics or else intolerance to the same. Two groups were independently analyzed, one consisting of ten patients who had menstrual migraine continually for twelve months, the other consisting of thirty-two patients suffering from migraine with and without aura for six months. We assessed the effectiveness of the drug (reduction in the intensity and duration of the attack, action, speed, recurrence) and tolerance (adverse effects). The effectiveness of sumatriptan in relieving headache was 75.9% (80% in the case of the menstrual migraine group and 71.8% in the case of the migraine with and without aura group). This effectiveness was maintained in a similar fashion by analyzing independently the first and last months of treatment. Adverse effects were noted in 38.7% of patients treated (40% for the menstrual migraine group, 37.5% for those with migraine with and without aura). The most frequent effects were pain at the point of injection, a feeling of general tiredness, nausea and a sensation of tension in the neck or chest. These effects were largely slight and short lived. No serious adverse effects were reported. A long term analysis carried out on the menstrual migraine group shows the efficacy of sumatriptan is kept up, with improved tolerance of the drug and a decrease in the number of negative side effects noted.(ABSTRACT TRUNCATED AT 250 WORDS) SN - 0210-0010 UR - https://www.unboundmedicine.com/medline/citation/7497233/[Subcutaneous_sumatriptan_in_the_treatment_of_migraine_attacks__An_analysis_of_its_long_term_efficaciousness_and_tolerance]_ L2 - http://www.diseaseinfosearch.org/result/4811 DB - PRIME DP - Unbound Medicine ER -