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Clinical and epidemiological characteristics of bleeding duodenal ulcer patients with and without dyspepsia.
Acta Med Croatica 1994; 48(4-5):175-8AM

Abstract

The most relevant clinical presentations of duodenal ulcer disease are pain and acute bleeding. The purpose of this study was to investigate the relevance of dyspepsia in patients with bleeding duodenal ulcer, and to compare the clinical and epidemiological characteristics of bleeding patients with and without dyspepsia. A total of 82 patients with isolated duodenal ulcer and bleeding were included in this study. There were 48 (58.5%) dyspeptic and 34 (41.5%) nondyspeptic patients. The patients with and without dyspepsia were almost identical with regard to their age (52.9 +/- 11.9 vs 53.4+/- 10.2 years, p > 0.05). In the dyspeptic group, significantly more patients had duodenitis and a deformed bulb (chi 2 = 4.05, p < 0.05 and chi 2 = 3.99, p < 0.05, respectively). Patients with bleeding duodenal ulcers and dyspepsia were more likely to have taken non-steroidal anti-inflammatory drugs (45.8 vs 8.8%; chi 2 = 11.18, p < 0.001), whereas significantly more patients in the nondyspeptic group have taken histamine H2 antagonists (85.3 vs 8.3%; chi 2 = 45.87, p < 0.01). No significant difference was found between the dyspeptic and nondyspeptic groups with regard to the previous diagnosis of peptic ulcer bleeding, the presence of environmental stress, gastritis, and alcohol or tobacco consumption. Furthermore, there was no significant difference in regard to the rebleeding, the need for urgent operation or hospital stay. The results of this study support the evidence that in patients with bleeding duodenal ulcers the dyspeptic symptoms were more often associated with objective signs of duodenal pathology, and the use of non-steroidal anti-inflammatory drugs and maintenance treatment with histamine H2 antagonists was associated with silent duodenal ulcer bleeding.

Authors+Show Affiliations

Department of Gastroenterology, Sveti Duh General Hospital, Zagreb, Croatia.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

7534520

Citation

Ljubicić, N, et al. "Clinical and Epidemiological Characteristics of Bleeding Duodenal Ulcer Patients With and Without Dyspepsia." Acta Medica Croatica : Casopis Hravatske Akademije Medicinskih Znanosti, vol. 48, no. 4-5, 1994, pp. 175-8.
Ljubicić N, Banić M, Brkić T. Clinical and epidemiological characteristics of bleeding duodenal ulcer patients with and without dyspepsia. Acta Med Croatica. 1994;48(4-5):175-8.
Ljubicić, N., Banić, M., & Brkić, T. (1994). Clinical and epidemiological characteristics of bleeding duodenal ulcer patients with and without dyspepsia. Acta Medica Croatica : Casopis Hravatske Akademije Medicinskih Znanosti, 48(4-5), pp. 175-8.
Ljubicić N, Banić M, Brkić T. Clinical and Epidemiological Characteristics of Bleeding Duodenal Ulcer Patients With and Without Dyspepsia. Acta Med Croatica. 1994;48(4-5):175-8. PubMed PMID: 7534520.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical and epidemiological characteristics of bleeding duodenal ulcer patients with and without dyspepsia. AU - Ljubicić,N, AU - Banić,M, AU - Brkić,T, PY - 1994/1/1/pubmed PY - 1994/1/1/medline PY - 1994/1/1/entrez SP - 175 EP - 8 JF - Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti JO - Acta Med Croatica VL - 48 IS - 4-5 N2 - The most relevant clinical presentations of duodenal ulcer disease are pain and acute bleeding. The purpose of this study was to investigate the relevance of dyspepsia in patients with bleeding duodenal ulcer, and to compare the clinical and epidemiological characteristics of bleeding patients with and without dyspepsia. A total of 82 patients with isolated duodenal ulcer and bleeding were included in this study. There were 48 (58.5%) dyspeptic and 34 (41.5%) nondyspeptic patients. The patients with and without dyspepsia were almost identical with regard to their age (52.9 +/- 11.9 vs 53.4+/- 10.2 years, p > 0.05). In the dyspeptic group, significantly more patients had duodenitis and a deformed bulb (chi 2 = 4.05, p < 0.05 and chi 2 = 3.99, p < 0.05, respectively). Patients with bleeding duodenal ulcers and dyspepsia were more likely to have taken non-steroidal anti-inflammatory drugs (45.8 vs 8.8%; chi 2 = 11.18, p < 0.001), whereas significantly more patients in the nondyspeptic group have taken histamine H2 antagonists (85.3 vs 8.3%; chi 2 = 45.87, p < 0.01). No significant difference was found between the dyspeptic and nondyspeptic groups with regard to the previous diagnosis of peptic ulcer bleeding, the presence of environmental stress, gastritis, and alcohol or tobacco consumption. Furthermore, there was no significant difference in regard to the rebleeding, the need for urgent operation or hospital stay. The results of this study support the evidence that in patients with bleeding duodenal ulcers the dyspeptic symptoms were more often associated with objective signs of duodenal pathology, and the use of non-steroidal anti-inflammatory drugs and maintenance treatment with histamine H2 antagonists was associated with silent duodenal ulcer bleeding. SN - 1330-0164 UR - https://www.unboundmedicine.com/medline/citation/7534520/Clinical_and_epidemiological_characteristics_of_bleeding_duodenal_ulcer_patients_with_and_without_dyspepsia_ L2 - http://www.diseaseinfosearch.org/result/2394 DB - PRIME DP - Unbound Medicine ER -