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Cutaneous microcirculation in skin lesions associated with chronic venous insufficiency.
Dermatol Surg. 1995 Oct; 21(10):877-82.DS

Abstract

BACKGROUND

There are various types of skin lesions in chronic venous insufficiency.

OBJECTIVE

To determine an association between different skin lesions and different changes in the cutaneous vascular bed.

METHODS

Twenty-eight patients with chronic venous insufficiency (CVI) without and with various types of skin lesions (ie, hyperpigmentation, lipodermatosclerosis, white atrophy, and venous ulcer) and 12 healthy control subjects were examined by video-capillaroscopy, transcutaneous oxygen tension measurement, photoplethysmography, and Doppler ultrasonography to detect disturbances of cutaneous microcirculation and venous macrocirculation.

RESULTS

There were no significant differences between the different CVI groups with respect to their venous function disorder. However, important variations were noted in the cutaneous microcirculation. In all the patient groups, an increase in the mean halo diameter could be demonstrated even in clinically healthy skin. In all types of skin lesions, the mean capillary diameter was significantly enlarged. Severe morphological capillary changes and a significant reduction of the mean transcutaneous oxygen tension values were found in conjunction with lipodermatosclerosis and white atrophy and in the areas surrounding venous ulcers.

CONCLUSION

The results of this study point to the conclusion that, once they have become established, microvascular disturbances play an independent role in the development of the skin lesions associated with CVI.

Authors+Show Affiliations

University Department of Dermatology, Ruhr University of Bochum, Germany.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

7551745

Citation

Stücker, M, et al. "Cutaneous Microcirculation in Skin Lesions Associated With Chronic Venous Insufficiency." Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.], vol. 21, no. 10, 1995, pp. 877-82.
Stücker M, Schöbe MC, Hoffmann K, et al. Cutaneous microcirculation in skin lesions associated with chronic venous insufficiency. Dermatol Surg. 1995;21(10):877-82.
Stücker, M., Schöbe, M. C., Hoffmann, K., & Schultz-Ehrenburg, U. (1995). Cutaneous microcirculation in skin lesions associated with chronic venous insufficiency. Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.], 21(10), 877-82.
Stücker M, et al. Cutaneous Microcirculation in Skin Lesions Associated With Chronic Venous Insufficiency. Dermatol Surg. 1995;21(10):877-82. PubMed PMID: 7551745.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cutaneous microcirculation in skin lesions associated with chronic venous insufficiency. AU - Stücker,M, AU - Schöbe,M C, AU - Hoffmann,K, AU - Schultz-Ehrenburg,U, PY - 1995/10/1/pubmed PY - 1995/10/1/medline PY - 1995/10/1/entrez SP - 877 EP - 82 JF - Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] JO - Dermatol Surg VL - 21 IS - 10 N2 - BACKGROUND: There are various types of skin lesions in chronic venous insufficiency. OBJECTIVE: To determine an association between different skin lesions and different changes in the cutaneous vascular bed. METHODS: Twenty-eight patients with chronic venous insufficiency (CVI) without and with various types of skin lesions (ie, hyperpigmentation, lipodermatosclerosis, white atrophy, and venous ulcer) and 12 healthy control subjects were examined by video-capillaroscopy, transcutaneous oxygen tension measurement, photoplethysmography, and Doppler ultrasonography to detect disturbances of cutaneous microcirculation and venous macrocirculation. RESULTS: There were no significant differences between the different CVI groups with respect to their venous function disorder. However, important variations were noted in the cutaneous microcirculation. In all the patient groups, an increase in the mean halo diameter could be demonstrated even in clinically healthy skin. In all types of skin lesions, the mean capillary diameter was significantly enlarged. Severe morphological capillary changes and a significant reduction of the mean transcutaneous oxygen tension values were found in conjunction with lipodermatosclerosis and white atrophy and in the areas surrounding venous ulcers. CONCLUSION: The results of this study point to the conclusion that, once they have become established, microvascular disturbances play an independent role in the development of the skin lesions associated with CVI. SN - 1076-0512 UR - https://www.unboundmedicine.com/medline/citation/7551745/Cutaneous_microcirculation_in_skin_lesions_associated_with_chronic_venous_insufficiency_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=1076-0512&date=1995&volume=21&issue=10&spage=877 DB - PRIME DP - Unbound Medicine ER -